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Pannus is an abnormal layer of fibrovascular tissue or granulation tissue. Common sites for pannus formation include over the cornea, over a joint surface (as seen in rheumatoid arthritis), or on a prosthetic heart valve. [1] Pannus may grow in a tumor-like fashion, as in joints where it may erode articular cartilage and bone.
This can lead to corneal opacities and scarring and then to blindness. Linear scars present in the sulcus subtarsalis [11] are called Arlt's lines (named after Carl Ferdinand von Arlt). In addition, blood vessels and scar tissue can invade the upper cornea (pannus). Resolved limbal follicles may leave small gaps in the pannus (Herbert's pits). [12]
Recurrent corneal erosions may occur. The hallmark of Schnyder corneal dystrophy is the accumulation of crystals within the corneal stroma which cause corneal clouding typically in a ring-shaped fashion. [citation needed] Posterior corneal dystrophies – Fuchs corneal dystrophy presents during the fifth or sixth decade of life. The ...
Most cases of recurrent corneal erosion are acquired. There is often a history of recent corneal injury, such as corneal abrasion or ulcer, but also may be idiopathic or due to corneal dystrophy or corneal disease. In other words, one may develop corneal erosions as a result of another disorder, such as epithelial basement membrane dystrophy ...
Conjunctival squamous cell carcinoma (conjunctival SCC) and corneal intraepithelial neoplasia comprise ocular surface squamous neoplasia (OSSN). SCC is the most common malignancy of the conjunctiva in the US, with a yearly incidence of 1–2.8 per 100,000.
The corneal limbus is the border between the cornea and the sclera. [1] It is highly vascularised. [1] Its stratified squamous epithelium is continuous with the epithelium covering the cornea. [2] The corneal limbus contains radially-oriented fibrovascular ridges known as the palisades of Vogt that contain limbal stem cells.
Keratitis is a condition in which the eye's cornea, the clear dome on the front surface of the eye, becomes inflamed. [1] The condition is often marked by moderate to intense pain and usually involves any of the following symptoms: pain, impaired eyesight, photophobia (light sensitivity), red eye and a 'gritty' sensation. [2]
The human cornea borders with the sclera at the corneal limbus. In lampreys , the cornea is solely an extension of the sclera, and is separate from the skin above it, but in more advanced vertebrates it is always fused with the skin to form a single structure, albeit one composed of multiple layers.