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A prolactinoma is a tumor of the pituitary gland that produces the hormone prolactin. It is the most common type of functioning pituitary tumor . [ 1 ] Symptoms of prolactinoma are due to abnormally high levels of prolactin in the blood ( hyperprolactinemia ), or due to pressure of the tumor on surrounding brain tissue and/or the optic nerves .
However, many other tumors of the pancreatic Islets of Langerhans can occur in MEN-1. One of these, involving the alpha cells, causes over-secretion of glucagon, resulting in a classic triad of high blood glucose levels (hyperglycemia), a rash called necrolytic migratory erythema, and weight loss.
How to Reset Female Hormones For Weight Loss. This article was reviewed by Craig Primack, MD, FACP, FAAP, MFOMA. Hormones can be helpful heroes, supporting the immune system and a healthy sleep ...
For instance, symptoms such as loss of libido and sexual dysfunction are subtle, arise gradually, and may falsely indicate a different cause. [11] Many men with pituitary tumor–associated hyperprolactinemia may forego clinical help until they begin to experience serious endocrine and vision complications, such as major headaches or eye ...
GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now. GLP-1s ...
It has a molecular weight of approximately 23-kDa. [55] It is a single-chain polypeptide of 199 amino acids and is apparently the result of removal of some amino acids. Big prolactin—approximately 48 kDa. [55] It may be the product of interaction of several prolactin molecules. It appears to have little, if any, biological activity. [56]
Prolactin cells are acidophilic by hematoxylin & eosin stains and, If these cells undergo neoplastic transformation, they will give rise to a prolactinoma, a prolactin-secreting pituitary adenoma. [3] Prolactinoma is a tumor of the pituitary gland that is typically non-cancerous. This disorder is more common in females than males.
Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. [1] [2] If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. [3]