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  2. History of penicillin - Wikipedia

    en.wikipedia.org/wiki/History_of_penicillin

    The history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins that became the first widely used antibiotics. Following the production of a relatively pure compound in 1942, penicillin was the first naturally-derived antibiotic.

  3. Penicillin - Wikipedia

    en.wikipedia.org/wiki/Penicillin

    Penicillin is actively excreted, and about 80% of a penicillin dose is cleared from the body within three to four hours of administration. Indeed, during the early penicillin era, the drug was so scarce and so highly valued that it became common to collect the urine from patients being treated, so that the penicillin in the urine could be ...

  4. Discovery of penicillin - Wikipedia

    en.wikipedia.org/wiki/Discovery_of_penicillin

    Sample of penicillin mould presented by Alexander Fleming to Douglas Macleod in 1935. The discovery of penicillin was one of the most important scientific discoveries in the history of medicine. Ancient societies used moulds to treat infections and in the following centuries many people observed the inhibition of bacterial growth by moulds.

  5. G. Raymond Rettew - Wikipedia

    en.wikipedia.org/wiki/G._Raymond_Rettew

    Granville Raymond Rettew (April 19, 1903 – June 24, 1973), known as G. Raymond Rettew, was an American chemist and mushroom spawn cultivator from Pennsylvania who pioneered the mass production of penicillin, the world’s first antibiotic. His methods helped save the lives of tens of thousands of wounded American and Allied troops during ...

  6. Alexander Fleming - Wikipedia

    en.wikipedia.org/wiki/Alexander_Fleming

    When it was finally recognized for what it was, the most efficacious life-saving drug in the world, penicillin would alter forever the treatment of bacterial infections. By the middle of the century, Fleming's discovery had spawned a huge pharmaceutical industry , churning out synthetic penicillins that would conquer some of mankind's most ...

  7. Ernest Duchesne - Wikipedia

    en.wikipedia.org/wiki/Ernest_Duchesne

    Ernest Duchesne (30 May 1874 – 12 April 1912) was a French physician who noted that certain molds kill bacteria.He made this discovery 32 years before Alexander Fleming discovered the antibiotic properties of penicillin, a substance derived from those molds, but his research went unnoticed.

  8. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Β-Lactam_antibiotic

    β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.

  9. AP World History: Modern - Wikipedia

    en.wikipedia.org/wiki/AP_World_History:_Modern

    The AP World History exam was first administered in 2002. The test underwent a major overhaul for the 2017 exam; however, due to the prodigious number of students that struggled with the free response section, the College Board decided to initiate yet another round of sweeping reform, to be put in effect in May 2018.