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Liraglutide, sold under the brand name Victoza among others, is an anti-diabetic medication used to treat type 2 diabetes, and chronic obesity. [6] [7] It is a second-line therapy for diabetes following first-line therapy with metformin. [6] [8] Its effects on long-term health outcomes like heart disease and life expectancy are unclear.
Victoza is FDA-approved to treat type 2 diabetes but is also sometimes prescribed off-label for weight loss. ... Kidney disease. Pancreatitis. Thyroid cancer, especially those with multiple ...
According to The Guardian, the wholesale acquisition cost (WAC) of the generic will be 13.6% lower than Victoza. A two-pack of injection pens is estimated to cost around $470, while a three-pack ...
It shows than to demonstrate a difference in all-cause cardiovascular death, non-fatal stroke, or limb amputation, but decreased the risk of nonfatal heart attack by 15%. [17] Additionally, tight glucose control decreased the risk of progression of kidney, nerve and eye complications, but increased the risk of hypoglycemia. [17]
Many folks opt to aim for the nice, square number of 1 gallon of water a day (for reference, 2.7 liters equal about 0.7 gallons), so we looked into the health benefits of drinking that much H20 ...
A renal diet is a diet aimed at keeping levels of fluids, electrolytes, and minerals balanced in the body in individuals with chronic kidney disease or who are on dialysis. Dietary changes may include the restriction of fluid intake, protein , and electrolytes including sodium , phosphorus , and potassium . [ 1 ]
Without such a concentrated medulla, water has less of an osmotic driving force to leave the collecting duct system, ultimately resulting in increased urine production. Loop diuretics cause a decrease in the renal blood flow by this mechanism. This diuresis leaves less water to be reabsorbed into the blood, resulting in a decrease in blood volume.
This included reductions in cardiovascular death, non-fatal heart attacks and strokes, compared to a placebo. The trial involved 9,650 patients with type 2 diabetes and either established cardiovascular disease or chronic kidney disease, using the drug alongside standard care. [57]
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