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In obstructive lung disease, the FEV1 is reduced due to an obstruction of air escaping from the lungs. Thus, the FEV1/FVC ratio will be reduced. [4] More specifically, according to the National Institute for Clinical Excellence, the diagnosis of COPD is made when the FEV 1 /FVC ratio is less than 0.7 or [8] the FEV 1 is less than 75% of predicted; [9] however, other authoritative bodies have ...
In combination with other physiological measurements, the vital capacity can help make a diagnosis of underlying lung disease. Furthermore, the vital capacity is used to determine the severity of respiratory muscle involvement in neuromuscular disease , and can guide treatment decisions in Guillain–Barré syndrome and myasthenic crisis .
Average values for forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1) and forced expiratory flow 25–75% (FEF25–75%), according to a study in the United States 2007 of 3,600 subjects aged 4–80 years. [12] Y-axis is expressed in litres for FVC and FEV1, and in litres/second for FEF25–75%.
The difference between the highest values of two FVCs need to be within 5% or 150 mL. When the FVC is less than 1.0 L, the difference between the highest two values must be within 100 mL. Lastly, the difference between the two highest values of FEV1 should also be within 150 mL. The highest FVC and FEV1 may be used from each different test.
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Online calculators are available that can compute predicted lung volumes, and other spirometric parameters based on a patient's age, height, weight, and ethnic origin for many reference sources. British rower and three-time Olympic gold medalist Pete Reed is reported to hold the largest recorded lung capacity of 11.68 litres; [ 16 ] [ 17 ] [ 18 ...
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For this reason, tables or charts are used to determine the normal value for a particular individual. More recently, medical calculators have been developed to calculate predicted values for peak expiratory flow. There are a number of non-equivalent scales used in the interpretation of peak expiratory flow.