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Failed shut-down: the inability of the body to shut off while stress accelerates and levels in the body exceed normal levels, for example, elevated blood pressure. Inadequate response: the failure of the body systems to respond to challenge, for example, excess levels of inflammation due to inadequate endogenous glucocorticoid responses.
Once the stressor is resolved, the body resumes to amounting an adequate immune and inflammatory response, which may explain why it is often seen that a person falls ill after acute stress. Due to the interconnected nature of the brain's regulation of stress, the immune system, and the endocrine system, allostasis may play a role in the ...
Definitions differ, and may be along the lines of continual activation of the stress response, [43] stress that causes an allostatic shift in bodily functions, [5] or just as "prolonged stress". [44] For example, results of one study demonstrated that individuals who reported relationship conflict lasting one month or longer have a greater risk ...
Decompensation may occur due to fatigue, stress, illness, or old age. When a system is "compensated," it is able to function despite stressors or defects. Decompensation describes an inability to compensate for these deficiencies. It is a general term commonly used in medicine to describe a variety of situations.
Hans Selye defined stress as “the nonspecific (that is, common) result of any demand upon the body, be the effect mental or somatic.” [5] This includes the medical definition of stress as a physical demand and the colloquial definition of stress as a psychological demand. A stressor is inherently neutral meaning that the same stressor can ...
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Cellular stress response is the wide range of molecular changes that cells undergo in response to environmental stressors, including extremes of temperature, exposure to toxins, and mechanical damage. Cellular stress responses can also be caused by some viral infections. [1]
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