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In April 2018, the first data set from the project was released, representing 530,000 immune system cells collected from bone marrow and cord blood. [ 11 ] A research program at the Max Planck Institute of Immunobiology and Epigenetics published an atlas of the cells of the liver , using single-cell RNA sequencing on 10,000 normal cells ...
Diagram showing the development of different blood cells from haematopoietic stem cell to mature cells. Haematopoiesis (/ h ɪ ˌ m æ t ə p ɔɪ ˈ iː s ɪ s, ˌ h iː m ə t oʊ-, ˌ h ɛ m ə-/; [1] [2] from Ancient Greek αἷμα (haîma) 'blood' and ποιεῖν (poieîn) 'to make'; also hematopoiesis in American English, sometimes h(a)emopoiesis) is the formation of blood cellular ...
The Human Cell Atlas project, which started in 2016, had as one of its goals to "catalog all cell types (for example, immune cells or brain cells) and sub-types in the human body". [13] By 2018, the Human Cell Atlas description based the project on the assumption that "our characterization of the hundreds of types and subtypes of cells in the ...
The global Human Cell Atlas consortium is developing and using experimental approaches to create comprehensive reference maps of all human cells as a basis for both understanding human health and ...
Red blood cells are circular, biconcave, disk-shaped and deformable to allow them to squeeze through narrow capillaries. They do not have a nucleus. Red blood cells are much smaller than most other human cells. RBCs are formed in the red bone marrow from hematopoietic stem cells in a process known as erythropoiesis. In adults, about 2.4 million ...
The normal bone marrow architecture can be damaged or displaced by aplastic anemia, malignancies such as multiple myeloma, or infections such as tuberculosis, leading to a decrease in the production of blood cells and blood platelets. The bone marrow can also be affected by various forms of leukemia, which attacks its hematologic progenitor ...
Myeloid tissue, in the bone marrow sense of the word myeloid (myelo-+ -oid), is tissue of bone marrow, of bone marrow cell lineage, or resembling bone marrow, and myelogenous tissue (myelo-+ -genous) is any tissue of, or arising from, bone marrow; in these senses the terms are usually used synonymously, as for example with chronic myeloid ...
The major function of the lungs is gas exchange between the lungs and the blood. [67] The alveolar and pulmonary capillary gases equilibrate across the thin blood–air barrier . [ 34 ] [ 68 ] [ 69 ] This thin membrane (about 0.5 –2 μm thick) is folded into about 300 million alveoli, providing an extremely large surface area (estimates ...