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Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.
Urea, also known as carbamide-containing cream, [clarification needed] is used as a medication and applied to the skin to treat dryness and itching such as may occur in psoriasis, dermatitis, or ichthyosis. [1] [2] [3] It may also be used to soften nails. [3] In adults side effects are generally few. [4] It may occasionally cause skin ...
To date, most sleep deprivation studies have focused on acute sleep deprivation, suggesting that acute sleep deprivation can cause significant damage to cognitive, emotional, and physical functions and brain mechanisms. [11] Few studies have compared the effects of acute total sleep deprivation and chronic partial sleep restriction. [8]
Doxepin is used in the treatment of insomnia. [11] In 2016, the American College of Physicians advised that insomnia be treated first by treating comorbid conditions, then with cognitive behavioral therapy and behavioral changes, and then with drugs; doxepin was among those recommended for short-term help maintaining sleep, on the basis of weak evidence.
A subsequent 1990 study found that the elimination half-life of diphenhydramine was 5.4 hours in children, 9.2 hours in young adults, and 13.5 hours in the elderly. [7] A 1998 study found a half-life of 4.1 ± 0.3 hours in young men, 7.4 ± 3.0 hours in elderly men, 4.4 ± 0.3 hours in young women, and 4.9 ± 0.6 hours in elderly women. [84] In ...
In medicine, a finger tip unit (FTU) is defined as the amount of ointment, cream or other semi-solid dosage form expressed from a tube with a 5 mm diameter nozzle, applied from the distal skin-crease to the tip of the index finger of an adult. [1] [2] The "distal skin-crease" is the skin crease over the joint nearest the end of the finger. One ...
A systematic review examined the benefits and clinical efficacy of routine skin care activities, such as washing, bathing, and applying lotions, in acute and long-term care adult settings. The study led to a proposed 2-step program targeting adults with intact or preclinically damaged skin. [13]
Obstructive sleep apnea, adult 327.23 G47.33 Obstructive sleep apnea, pediatric 327.23 G47.33 Sleep-related hypoventilation/hypoxemic syndromes: Sleep-related non-obstructive alveolar hypoventilation, bidiopathic 327.24 G47.34 Congenital central alveolar hypoventilation syndrome 327.25 G47.35 Sleep-related hypoventilation/hypoxemia due to a ...