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The 11 species in this genus include human betaherpesvirus 5 (HCMV, human cytomegalovirus, HHV-5), which is the species that infects humans. Diseases associated with HHV-5 include mononucleosis and pneumonia, [4] [5] and congenital CMV in infants can lead to deafness and ambulatory problems. [6]
The mobilome is the entire set of mobile genetic elements in a genome. Mobilomes are found in eukaryotes, [1] prokaryotes, [2] and viruses. [3] The compositions of mobilomes differ among lineages of life, with transposable elements being the major mobile elements in eukaryotes, and plasmids and prophages being the major types in prokaryotes. [4]
How viruses do this depends mainly on the type of nucleic acid DNA or RNA they contain, which is either one or the other but never both. Viruses cannot function or reproduce outside a cell, and are totally dependent on a host cell to survive. Most viruses are species specific, and related viruses typically only infect a narrow range of plants ...
Total genome length is of one monomer ranges from 8k-10k nt (depending on the virus). Genome sequence has terminal repeated sequences; long terminal repeats (LTR) (of about 600 nt) The 5' end of the genome has a cap; Cap sequence of type 1 m7G5ppp5'GmpNp; 3' end of each monomer has a poly (A) tract.
A variety of amino acid changes in the UL97 protein kinase and the viral DNA polymerase have been reported to cause drug resistance. Foscarnet or cidofovir are only given to people with CMV resistant to ganciclovir, because foscarnet has notable nephrotoxicity, resulting in increased or decreased Ca 2+ or PO 4 3−, and decreased Mg 2+ levels ...
Member viruses infect arthropods, plants, protozoans, and vertebrates. [2] It is the only order in the class Ellioviricetes. [1] The name Bunyavirales derives from Bunyamwera, [3] where the original type species Bunyamwera orthobunyavirus was first discovered. [4]
The genus includes human pathogens like Zika virus, West-Nile virus, Dengue virus, Yellow Fever virus and other. [ 1 ] The 5' UTR of flaviviruses are highly structured, has a length of approximately 100 nucleotides and harbors two conserved RNA secondary structures which are vital for the viral life cycle.
Caulimoviridae is a family of viruses infecting plants. [1] There are 94 species in this family, assigned to 11 genera. [2] [3] Viruses belonging to the family Caulimoviridae are termed double-stranded DNA (dsDNA) reverse-transcribing viruses (or pararetroviruses) i.e. viruses that contain a reverse transcription stage in their replication cycle.