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Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Naltrexone-bupropion. An FDA-approved weight loss medication, ... This is a combination of an appetite suppressant called phentermine and an anticonvulsant called topiramate.
This is not much different from the weight loss produced by several other weight-loss medications such as sibutramine or orlistat. [74] The combination drug naltrexone/bupropion has been approved by the US Food and Drug Administration (FDA) for the treatment of obesity. [75] [76]
Naltrexone-bupropion (Contrave) is a two-in-one combination that can help with weight loss. Used together these drugs may help reduce appetite and help control cravings. Research shows that ...
Regular physical activity can help accelerate weight loss, improve metabolism and enhance the benefits of weight loss pills. Aim for 150 minutes per week (or about a half-hour five days a week).
Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
Alternatively, switching from a more modern type of antidepressant, such as an SSRI or SNRI, to an antidepressant for weight loss, such as bupropion, may also produce improvements.
The medications liraglutide, [4] naltrexone/bupropion, [5] orlistat, [6] semaglutide, [7] and tirzepatide [8] are approved by the US Food and Drug Administration (FDA) for weight management in combination with reduced-calorie diet and increased physical activity.
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