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Repaglinide is a major substrate of CYP3A4 and should not be administered concomitantly with gemfibrozil, clarithromycin or azole antifungals such as itraconazole or ketoconazole. [1] Administration of both repaglinide and one or more of these drugs results in an increase in plasma concentration of repaglinide and may lead to hypoglycemia.
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Glimepiride is an antidiabetic medication within the sulfonylurea class, primarily prescribed for the management of type 2 diabetes. [ 1 ] [ 2 ] It is regarded as a second-line option compared to metformin , due to metformin's well-established safety and efficacy. [ 1 ]
For this study, researchers analyzed medical data from almost 394,000 adults 40 years and older with type 2 diabetes and active COPD that were taking GLP-1, SGLT-2, or DPP-4i medications.
Diabetes, a condition where blood glucose levels cannot be controlled, affects more than 10% of the adult population worldwide, and more than 90% of those have type 2 diabetes.
Repaglinide (trade name Prandin) [2] gained US Food and Drug Administration approval in 1997. Other drugs in this class include nateglinide (Starlix) [ 3 ] and mitiglinide (Glufast). Side effects
In one study of people on liraglutide (Saxenda), those who lifted four times a week held on to muscle mass better than those who only took meds or only exercised. Also, “make sure your new diet ...
Drugs used in diabetes treat types of diabetes mellitus by decreasing glucose levels in the blood.With the exception of insulin, most GLP-1 receptor agonists (liraglutide, exenatide, and others), and pramlintide, all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents.