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The bladder tumour antigen (BTA) test is used in the detection of bladder cancer.It works by detecting raised levels of complement factor Hârelated protein (CFHrp), which is produced by cancer cells, in urine.
Diagram showing the T stages of bladder cancer. Date: 30 July 2014 (released by CRUK) Source: Original email from CRUK: Author: Cancer Research UK: Permission (Reusing this file) This image has been released as part of an open knowledge project by Cancer Research UK. If re-used, attribute to Cancer Research UK / Wikimedia Commons
Bladder cancer is much more common in men than women; around 1.1% of men and 0.27% of women develop bladder cancer. [2] This makes bladder cancer the sixth most common cancer in men, and the seventeenth in women. [69] When women are diagnosed with bladder cancer, they tend to have more advanced disease and consequently a poorer prognosis. [69]
Tumor markers can be molecules that are produced in higher amounts by cancer cells than normal cells, but can also be produced by other cells from a reaction with the cancer. [2] The markers can't be used to give patients a diagnosis but can be compared with the result of other tests like biopsy or imaging. [2]
loss of bladder control (incontinence) or overactive bladder; (Although, the American Urogynecologic Society does not recommend that cystoscopy, urodynamics, or diagnostic renal and bladder ultrasound are part of initial diagnosis for uncomplicated overactive bladder.) [2] [3] unusual cells found in urine sample; need for a bladder catheter;
The test commonly checks for infection, inflammatory disease of the urinary tract, cancer, or precancerous conditions. It can be part of a broader urinalysis . If a cancerous condition is detected, other tests and procedures are usually recommended to diagnose cancers, including bladder cancer , ureteral cancer and cancer of the urethra .
Evidence is insufficient to recommend for or against screening for skin cancer, [167] oral cancer, [168] lung cancer, [169] or prostate cancer in men under 75. [170] Routine screening is not recommended for bladder cancer, [171] testicular cancer, [172] ovarian cancer, [173] pancreatic cancer, [174] or prostate cancer. [175]
In men aged 55–69 who have been counseled on the known harms and potential benefits of prostate cancer screening, the U.S. Preventive Service Task Force May 2018 statement states, "The use of digital rectal examination as a screening modality is not recommended because there is a lack of evidence on the benefits."
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