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  2. Epidermis - Wikipedia

    en.wikipedia.org/wiki/Epidermis

    Most of the barrier functions of the epidermis localize to this layer. [12] clear/translucent layer (stratum lucidum, only in palms and soles) This narrow layer is found only on the palms and soles. The epidermis of these two areas is known as "thick skin" because with this extra layer, the skin has 5 epidermal layers instead of 4.

  3. Human skin - Wikipedia

    en.wikipedia.org/wiki/Human_skin

    Tissue mass is defined at 3.3 kg (ICRP-89, ICRP110) and addresses the skin's epidermis, dermis, hair follicles, and glands. The cell data is extracted from 'The Human Cell Count and Cell Size Distribution', [17] [18] Tissue-Table tab in the Supporting Information SO1 Dataset (xlsx). The 1200 record Dataset is supported by extensive references ...

  4. Stratum corneum - Wikipedia

    en.wikipedia.org/wiki/Stratum_corneum

    An inability to correctly maintain the skin barrier function due to the dysregulation of epidermal components can lead to skin disorders. For example, a failure to modulate the activity of kallikreins via the disruption of the protease inhibitor LEKTI causes the debilitating disorder Netherton syndrome. [11]

  5. Integumentary system - Wikipedia

    en.wikipedia.org/wiki/Integumentary_system

    The human epidermis is composed of stratified squamous epithelial cells, which further break down into four to five layers: the stratum corneum, stratum granulosum, stratum spinosum and stratum basale. Where the skin is thicker, such as in the palms and soles, there is an extra layer of skin between the stratum corneum and the stratum ...

  6. Stratified squamous epithelium - Wikipedia

    en.wikipedia.org/wiki/Stratified_squamous_epithelium

    It forms the outermost layer of the skin and the inner lining of the mouth, esophagus and vagina. [2] In the epidermis of skin in mammals, reptiles, and birds, the layer of keratin in the outer layer of the stratified squamous epithelial surface is named the stratum corneum. Stratum corneum is made up of squamous cells which are keratinized and ...

  7. Keratinocyte - Wikipedia

    en.wikipedia.org/wiki/Keratinocyte

    Micrograph of keratinocytes, basal cells and melanocytes in the epidermis Keratinocytes (stained green) in the skin of a mouse. Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells. [1]

  8. Skin - Wikipedia

    en.wikipedia.org/wiki/Skin

    Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings , such as the arthropod exoskeleton , have different developmental origin , structure and chemical composition .

  9. Corneocyte - Wikipedia

    en.wikipedia.org/wiki/Corneocyte

    Corneocytes are terminally differentiated keratinocytes and compose most of the stratum corneum, the outermost layer of the epidermis.They are regularly replaced through desquamation and renewal from lower epidermal layers and are essential for its function as a skin barrier.