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However, if properly assessed, secondary negative symptoms are amenable to treatment. [46] There is some evidence that the negative symptoms of schizophrenia are amenable to psychostimulant medication, although such drugs have varying degrees of risk for causing positive psychotic symptoms. [53]
Cannabis is a known risk factor for developing psychosis that can progress to schizophrenia but this is the first time researchers have found brain-level changes in an at-risk population in real time.
The risk of enlarged ventricles on brain scan (associated with schizophrenia symptoms and biologically suggestive of Emil Kraepelin's dementia praecox) was greatly increased if the subjects had both a higher genetic load for schizophrenia and lower birthweight. The investigators suggested that in utero insults may specifically stress those with ...
In schizophrenia, asociality is one of the main five "negative symptoms", with the others being avolition, anhedonia, reduced affect, and alogia. Due to a lack of desire to form relationships, social withdrawal is common in people with schizophrenia.
Symptoms of schizophrenia simplex include an absence of will, impoverished thinking and flattening of affect. There is a gradual deterioration of functioning with increased amotivation and reduced socialization. [6] [7] It is considered to be rarely diagnosed and is a schizophrenia without psychotic symptoms. [8]
Positive symptoms are present at a low intensity and negative symptoms are prominent. Residual type (295.6) Simple (F20.6) Delusions and hallucinations are not evident and negative symptoms progress slowly. Not present Other (F20.8) Includes cenesthopathic schizophrenia and schizophreniform disorder NOS Not present
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