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The loop electrosurgical excision procedure (LEEP) is one of the most commonly used approaches to treat high grade cervical dysplasia (CIN II/III, HGSIL) and early stage cervical cancer discovered on colposcopic examination. In the UK, it is known as large loop excision of the transformation zone (LLETZ).
Colposcopy (Ancient Greek: κόλπος, romanized: kolpos, lit. 'hollow, womb, vagina' + skopos 'look at') is a medical diagnostic procedure to visually examine the cervix as well as the vagina and vulva using a colposcope. [1] The main goal of colposcopy is to prevent cervical cancer by detecting and treating precancerous lesions early.
LEEP cone biopsy displaying normal cervical epithelium (far left) progressing to borderline koilocytosis, to LSIL, and to HSIL (far right). In LSIL of the cervix, definitive koilocytes are present. In addition, squamous cells commonly display binucleation and mitoses are present, signifying increased cellular division. [ 7 ]
Colposcopy; Dilation and Curettage (D&C) Hysteroscopy; LEEP procedure; Pelvic laparoscopy; Gynecologic surgeries. Gynecological surgery includes: [medical citation ...
The typical threshold for treatment is CIN 2+, although a more restrained approach may be taken for young persons and pregnant women. Treatment for higher-grade CIN involves removal or destruction of the abnormal cervical cells by cryocautery, electrocautery, laser cautery, loop electrical excision procedure (LEEP), or cervical conization. [21]
LEEP cone biopsy displaying normal cervical epithelium (far left) progressing to borderline koilocytosis, to LSIL, and to HSIL (far right). A squamous intraepithelial lesion (SIL) is an abnormal growth of epithelial cells on the surface of the cervix, commonly called squamous cells.
Cervical conization refers to an excision of a cone-shaped portion of tissue from the mucous membrane of the cervix.Conization is used for diagnostic purposes as part of a biopsy and for therapeutic purposes to remove pre-cancerous cells (cervical intraepithelial neoplasia) or early stage cervical cancer.
Because of this, LSIL results can be managed with a simple "watch and wait" philosophy. However, because there is a 12–16% chance of progression to more severe dysplasia, the physician may want to follow the results more aggressively by performing a colposcopy with biopsy. [7] If the dysplasia progresses, treatment may be necessary.