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For example, in clinical trials, the drug strontium ranelate was found to aid bone growth, increase bone density, and lessen vertebral, peripheral, and hip fractures in women. Strontium ranelate is an antiosteoporotic agent which both increases bone formation and reduces bone resorption, resulting in a rebalance of bone turnover in favor of ...
Stress is applied to the bones, thus activating osteoblast, which are cells that form new bones and grow and heal existing bones [159] while restoring hormones that increase bone density. Resistance training exercises, like weight lifting, can lead to brief increased in anabolic hormones, like testosterone, which aid in muscle and bone strength ...
The former has a half-life of 50.6 days and is used to treat bone cancer due to strontium's chemical similarity and hence ability to replace calcium. [23] [24] While 90 Sr (half-life 28.90 years) has been used similarly, it is also an isotope of concern in fallout from nuclear weapons and nuclear accidents due to its production as a fission ...
Bone mineral density (BMD) is a measure commonly used to quantify bone health. A lower BMD value indicates an increased risk of an osteoporosis or a fracture. [13] There is a large range of factors influencing BMD. Protein consumption has shown to be beneficial for bone density by providing amino acid substrates necessary for bone matrix formation.
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A bone seeker is an element, often a radioisotope, that tends to accumulate in the bones of humans and other animals when introduced into the body. For example, strontium and radium are chemically similar to calcium and can replace the calcium in bones.
The inverse is true as well: if the loading on a bone decreases, the bone will become less dense and weaker due to the lack of the stimulus required for continued remodeling. [5] This reduction in bone density is known as stress shielding and can occur as a result of a hip replacement (or other prosthesis).
Examples of periosteal reactive bone in selected specimens of Triceratops. A periosteal reaction can result from a large number of causes, including injury and chronic irritation due to a medical condition such as hypertrophic osteopathy, bone healing in response to fracture, chronic stress injuries, subperiosteal hematomas, osteomyelitis, and cancer of the bone.