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The Indonesian Food and Drug Authority (Indonesian: Badan Pengawas Obat dan Makanan, lit. 'Food and Drug Supervisory Agency'), Badan POM/BPOM, or Indonesian FDA is a government agency of Indonesia responsible for protecting public health through the control and supervision of prescription and over-the-counter pharmaceutical drugs (medication), vaccines, biopharmaceuticals, dietary supplements ...
IndoVac is a recombinant protein subunit COVID-19 vaccine, [1] [2] developed by Indonesian pharmaceutical company Bio Farma and Baylor College of Medicine in Houston, Texas. [1] [2] It is the world's first officially halal certified COVID-19 vaccine, [3] but the most popular existing vaccines had already been widely endorsed as Halal by various ...
The Enzyme Commission refers to this family as SARS coronavirus main proteinase (M pro; EC 3.4.22.69). The 3CL protease corresponds to coronavirus nonstructural protein 5 (nsp5). The "3C" in the common name refers to the 3C protease (3C pro ) which is a homologous protease found in picornaviruses .
The general idea behind modern antiviral drug design is to identify viral proteins, or parts of proteins, that can be disabled. [11] [13] These "targets" should generally be as unlike any proteins or parts of proteins in humans as possible, to reduce the likelihood of side effects and toxicity. [8]
The commission is the lead agency in mainland China coordinating the national efforts to combat the COVID-19 pandemic. [5]On 11 February 2020, in order to manage the ongoing health crisis, the following changes were announced [6] by the NHC:
Environment, health and safety (EHS) (or health, safety and environment –HSE–, or safety, health and environment –SHE–) is an interdisciplinary field focused on the study and implementation of practical aspects environmental protection and safeguard of people's health and safety, especially in an occupational context.
SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E, NL63, OC43, HKU1, MERS-CoV, and the original SARS-CoV. [105] Like the SARS-related coronavirus implicated in the 2003 SARS outbreak, SARS‑CoV‑2 is a member of the subgenus Sarbecovirus (beta-CoV lineage B). [106] [107] Coronaviruses undergo frequent recombination. [108]
The COVID-19 vaccines are widely credited for their role in reducing the severity and death caused by COVID-19. [ 128 ] [ 129 ] As of March 2023, more than 5.5 billion people had received one or more doses [ 130 ] (11.8 billion in total) in over 197 countries.