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Pirenoxine (abbreviated PRX, trade name Catalin) is a medication used in the possible treatment and prevention of cataracts. A report in the Inorganic Chemistry journal s howed that in liquid solutions, pirenoxine could cause decreased cloudiness of a crystallin solution produced to mimic the environment of the eye.
Cataract is globally the most common cause of blindness in people older than 50 years. It impairs vision and lowers quality of life. Improvements in vision help with daily activities, including work productivity and education. Cataract surgery reduces risk of falling and of dementia.
A 2013 American survey involving nearly two million bilateral cataract surgery patients found immediate sequential bilateral cataract surgery was statistically associated with worse visual outcomes than for delayed sequential bilateral cataract surgery; however, the difference was small and might not be clinically relevant. [100]
A recent 2000 study in Munich, Germany analyzed the activity levels of the GALE enzyme in various tissues and cells in patients with cataract. The experiment concluded that while patients with cataract seldom exhibited an acute decrease in GALE activity in blood cells , "the GALE activity in the lens of cataract patients was, on the other hand ...
Visual or vision impairment (VI or VIP) is the partial or total inability of visual perception.In the absence of treatment such as corrective eyewear, assistive devices, and medical treatment, visual impairment may cause the individual difficulties with normal daily tasks, including reading and walking. [6]
Patients who undergo a standard IOL implantation no longer experience clouding from cataracts, but they are unable to accommodate (change focus from near to far, far to near, and to distances in between). This is not a concern for most cataract surgeries, as they are primarily performed on elderly people that are already completely presbyopic ...
Myotonic dystrophy affects about 1 in 2,100 people, [4] a number that was long estimated to be much lower (often cited as 1 in 8,000), reflecting that not all patients have immediate symptoms and, once they do have symptoms, the long time it typically takes to get to the right diagnosis. [1]
However, perimetry and microperimetry studies indicate that the peripheral light sensitivity is preserved over a long time in a significant fraction of all patients (i.e., >50%). [7] [20] Stargardt disease has no impact on general health and life expectancy is normal. [21]
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