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  2. Myostatin - Wikipedia

    en.wikipedia.org/wiki/Myostatin

    Myostatin (also known as growth differentiation factor 8, abbreviated GDF8) is a protein that in humans is encoded by the MSTN gene. [6] Myostatin is a myokine that is produced and released by myocytes and acts on muscle cells to inhibit muscle growth. [7] Myostatin is a secreted growth differentiation factor that is a member of the TGF beta ...

  3. Statin-associated autoimmune myopathy - Wikipedia

    en.wikipedia.org/wiki/Statin-associated...

    SAAM may affect people after long-term statin use even if they had no previous muscular side effects. [4] A differentiating feature between this and more benign statin side effects is SAAM typically has a late onset. While muscle pain (myalgia) is seen in 9-20% of patients treated with statins, it typically occurs in the first month of treatment.

  4. Acquired non-inflammatory myopathy - Wikipedia

    en.wikipedia.org/wiki/Acquired_non-inflammatory...

    Common types of myopathy due to statins include myalgia, myositis, and rhabdomyolysis. Statins induce myopathy by inhibiting protein synthesis within the muscle. [6] Statin therapy tends to not show any histopathological differences, and thus a biopsy does not reveal too much about the damage. Often, the damage is found within the mitochondria.

  5. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    The most important adverse side effects are muscle problems, an increased risk of diabetes mellitus, and increased liver enzymes in the blood due to liver damage. [5] [65] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke, and 5 cases of muscle damage per 10,000 people treated. [34]

  6. Rhabdomyolysis - Wikipedia

    en.wikipedia.org/wiki/Rhabdomyolysis

    Statins (prescription drugs to lower cholesterol) are considered a small risk. [9] Some people have inherited muscle conditions that increase the risk of rhabdomyolysis. [3] The diagnosis is supported by a urine test strip which is positive for "blood" but the urine contains no red blood cells when examined with a microscope. [3]

  7. Myostatin-related muscle hypertrophy - Wikipedia

    en.wikipedia.org/wiki/Myostatin-related_muscle...

    Myostatin-related muscle hypertrophy is a rare genetic condition characterized by reduced body fat and increased skeletal muscle size. [1] Affected individuals have up to twice the usual amount of muscle mass in their bodies, but increases in muscle strength are not usually congruent. [ 2 ]

  8. Canine physical therapy - Wikipedia

    en.wikipedia.org/wiki/Canine_physical_therapy

    The benefits of physical therapy for animals have been widely accepted in the veterinary community for many years. [10] [11] [12] However, clinical practice of physical therapy for animals is a relatively new field in the U.S. In Europe, equine and canine physical therapy have been widely recommended and used for at least the last fifteen years ...

  9. Rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Rosuvastatin

    Common side effects include abdominal pain, nausea, headaches, and muscle pains. [6] Serious side effects may include rhabdomyolysis, liver problems, and diabetes. [6] Use during pregnancy may harm the baby. [6] Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing ...