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  2. Serum protein electrophoresis - Wikipedia

    en.wikipedia.org/wiki/Serum_protein_electrophoresis

    The immunoglobulins or antibodies are generally the only proteins present in the normal gamma region. Of note, any protein migrating in the gamma region will be stained and appear on the gel, which may include protein contaminants, artifacts, or certain medications. Depending on whether an agarose or capillary method is used, interferences vary.

  3. Myeloma protein - Wikipedia

    en.wikipedia.org/wiki/Myeloma_protein

    Serum protein electrophoresis showing a paraprotein (spike/peak in the gamma zone) in a patient with multiple myeloma.. A myeloma protein is an abnormal antibody (immunoglobulin) or (more often) a fragment thereof, such as an immunoglobulin light chain, that is produced in excess by an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonal gammopathy of ...

  4. Monoclonal gammopathy of undetermined significance - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_gammopathy_of...

    MGUS resembles multiple myeloma and similar diseases, but the levels of antibodies are lower, [2] the number of plasma cells (white blood cells that secrete antibodies) in the bone marrow is lower, and it rarely has symptoms or major problems. However, since MGUS can lead to multiple myeloma, which develops at the rate of about 1.5% a year, or ...

  5. Multiple myeloma - Wikipedia

    en.wikipedia.org/wiki/Multiple_myeloma

    Multiple myeloma is the second-most prevalent blood cancer (10%) after non-Hodgkin's lymphoma. [154] It represents about 1.8% of all new cancers and 2.1% of all cancer deaths. [7] Multiple myeloma affects slightly more men than women.

  6. Bortezomib - Wikipedia

    en.wikipedia.org/wiki/Bortezomib

    Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. [4] This includes multiple myeloma in those who have and have not previously received treatment. [3] It is generally used together with other medications. [3] It is given by injection. [4]

  7. Lenalidomide - Wikipedia

    en.wikipedia.org/wiki/Lenalidomide

    For multiple myeloma, it is a first line treatment, and is given with dexamethasone. [8] It is taken by mouth. [8] Common side effects include diarrhea, itchiness, joint pain, fever, headache, and trouble sleeping. [8] Severe side effects include low blood platelets, low white blood cells, and blood clots. [8]

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