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The AIDS epidemic, caused by HIV (Human Immunodeficiency Virus), found its way to the United States between the 1970s and 1980s, [2] but was first noticed after doctors discovered clusters of Kaposi's sarcoma and pneumocystis pneumonia in homosexual men in Los Angeles, New York City, and San Francisco in 1981.
The global pandemic of HIV/AIDS (human immunodeficiency virus infection and acquired immunodeficiency syndrome) began in 1981, and is an ongoing worldwide public health issue. [ 4 ] [ 5 ] [ 6 ] According to the World Health Organization (WHO), by 2023, HIV/AIDS had killed approximately 40.4 million people, and approximately 39 million people ...
Despite these statistics, overall, new HIV infections and AIDS-related deaths have substantially decreased in this region since 2010. [228] Eastern Europe and central Asia has observed a 43% increase in new HIV infections and 32% increase in AIDS-related deaths since 2010, the highest of all global regions. [228]
African-Americans are at the highest risk of contracting HIV in the United States. According to the Centers for Disease and Control and Prevention (CDC), African-American accounted for 44% of all new HIV infections in the United States between 2010 and 2016, although African-Americans make up roughly 12% of the American population. [3]
The human immunodeficiency viruses (HIV) are two species of Lentivirus (a subgroup of retrovirus) that infect humans.Over time, they cause acquired immunodeficiency syndrome (AIDS), [1] [2] a condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. [3]
Adult HIV prevalence exceeds 20% in Eswatini, Botswana, Lesotho and Zimbabwe, while an additional five countries report adult HIV prevalence of at least 10%. In absolute numbers, South Africa (9.2 million), followed Tanzania (2.55 million) and Mozambique (2.48 million) and Nigeria (2.45million) had the highest HIV/AIDS number of cases by the ...
[6] [7] However, the most researched cause of cardiomyopathy is myocarditis (myocardial inflammation and infection) caused by HIV-1, which the main subtype of HIV (the other being HIV-2), with greater likelihood of transmission and shorter period between infection and illness. HIV-1 virions infect cardiomyocytes in patches but there is no ...
CD4 T-cell depletion and chronic inflammation are the two signature events that drive HIV pathogenesis and progression to AIDS. Infection of the cells of the CNS cause acute aseptic meningitis, subacute encephalitis, vacuolar myelopathy and peripheral neuropathy. Later it leads to even AIDS dementia complex.
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