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In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment.
Medications that may cause or worsen the disease include benzodiazepines, calcium channel blockers, tricyclic antidepressants, NSAIDs, and certain asthma medicines. Acid reflux is due to poor closure of the lower esophageal sphincter, which is at the junction between the stomach and the esophagus.
There are several classes of drugs for acid-related disorders, such as dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD), or laryngopharyngeal reflux. The World Health Organization gives drugs in these classes the categorization code ATC code A02 .
The angle of His forms an anatomical sphincter. This prevents the reflux of stomach acid, digestive enzymes, and duodenal bile from entering the esophagus. [4] [5] This is important in preventing gastroesophageal reflux disease and inflammation of the esophagus. [5]
It can be caused by or associated with gastroesophageal reflux disease, [1] esophagitis, a dysfunctional lower esophageal sphincter, disordered motility, lye ingestion, or a hiatal hernia. Strictures can form after esophageal surgery and other treatments such as laser therapy or photodynamic therapy. While the area heals, a scar forms, causing ...
In the case of individuals fed by gastric tube, acid may enter the oral cavity through reflux of gastric contents. Gastroesophageal reflux disease (GERD) affects up to 67% of children and young adults with central nervous system dysfunction, a condition which in itself is normally an indicator for tube feeding. The effects of gastric acid on ...
In medicine, pink lady is a term used for a combination of medications used to treat gastroesophageal reflux or gastritis. It usually consists of an antacid and the anaesthetic lidocaine. Some variants contain an anticholinergic. The name of the preparation comes from its colour – pink.
Diagnosis is made on the basis of the association of gastro-oesophageal reflux with the characteristic movement disorder. Neurological examination is usually normal. Misdiagnosis as benign infantile spasms or epileptic seizures is common, particularly where clear signs or symptoms of gastro-oesophageal reflux are not apparent.
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