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L-Glycine ball and stick model spinning. Glycine (symbol Gly or G; [6] / ˈ ɡ l aɪ s iː n / ⓘ) [7] is an amino acid that has a single hydrogen atom as its side chain.It is the simplest stable amino acid.
In water, measurable pK a values range from about −2 for a strong acid to about 12 for a very weak acid (or strong base). A buffer solution of a desired pH can be prepared as a mixture of a weak acid and its conjugate base.
The complete data for Glycine. General information. Chemical formula: C 2 H 5 N O 2 ...
In glycine the pK values are separated by nearly 7 units. Thus in the gas phase, the concentration of the neutral species, glycine (GlyH), is effectively 100% of the analytical glycine concentration. [6] Glycine may exist as a zwitterion at the isoelectric point, but the equilibrium constant for the isomerization reaction in solution
The first (e.g., acetic acid or ammonium) have only one dissociable group, the second (e.g., carbonic acid, bicarbonate, glycine) have two dissociable groups and the third (e.g., phosphoric acid) have three dissociable groups. In the case of multiple pK values they are designated by indices: pK 1, pK 2, pK 3 and so on.
The following table presents pK a values at 20 °C. Values change by about 0.01 per degree of temperature. [1] [3] Good's original 1966 paper had two older buffers (marked with italics) for comparison. In 1972 Good published a second list with three more buffers, and five more were added in 1980.
It is one of Good's buffers and has a pKa of 8.35 at 20 °C. [1] It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone. [2] Bicine is a contaminant in amine systems used for gas sweetening. It is formed by amine degradation in the presence of O 2, SO 2, H 2 S or Thiosulfate. [3]
Glycylglycine is the dipeptide of glycine, making it the simplest peptide. [1] The compound was first synthesized by Emil Fischer and Ernest Fourneau in 1901 by boiling 2,5-diketopiperazine (glycine anhydride) with hydrochloric acid. [2] Shaking with alkali [1] and other synthesis methods have been reported. [3]