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Intra-cellular features are characteristic of a synthetically active cell. The cell density of full-thickness, human, adult, femoral condyle cartilage is maintained at 14.5 (±3.0) × 10 3 cells/ mm 2 from age 20 to 30 years. Although chondrocyte senescence occurs with aging, mitotic figures are not seen in normal adult articular cartilage.
Each lacuna is occupied during life by a branched cell, termed an osteocyte, bone-cell or bone-corpuscle. Lacunae are connected to one another by small canals called canaliculi. A lacuna never contains more than one osteocyte. Sinuses are an example of lacuna.
The cell body varies in size from 5–20 micrometers in diameter and contain 40–60 cell processes per cell, [4] with a cell to cell distance between 20–30 micrometers. [3] A mature osteocyte contains a single nucleus that is located toward the vascular side and has one or two nucleoli and a membrane. [ 5 ]
The Haversian canals surround blood vessels and nerve cells throughout bones and communicate with osteocytes (contained in spaces within the dense bone matrix called lacunae) through connections called canaliculi. This unique arrangement is conducive to mineral salt deposits and storage which gives bone tissue its strength.
Diameter of canaliculi in human bone is approximately 200 to 900 nm. [1] In bovine tibia diameter of canaliculi was found to vary from 155 to 844 nm (average 426 nm). [ 2 ] In mice humeri it varies from 80 to 710 nm (average 259 nm), while diameter of osteocytic processes varies from 50 to 410 nm (average 104 nm).
At a site of active bone resorption, the osteoclast forms a specialized cell membrane, the "ruffled border", that opposes the surface of the bone tissue. This extensively folded or ruffled border facilitates bone removal by dramatically increasing the cell surface for secretion and uptake of the resorption compartment contents and is a ...
A special type of Reed–Sternberg cell (RSC) is the lacunar histiocyte, whose cytoplasm retracts when fixed in formalin, so the nuclei give the appearance of cells that lie with empty spaces (called lacunae) between them. [4] These are characteristic of the nodular sclerosis subtype of Hodgkin lymphoma. [4]
Aerenchyma in stem cross section of a typical wetland plant. Aerenchyma or aeriferous parenchyma [1] or lacunae, is a modification of the parenchyma to form a spongy tissue that creates spaces or air channels in the leaves, stems and roots of some plants, which allows exchange of gases between the shoot and the root. [2]