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Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues. [1] The knee joint is most commonly affected. [2]
A magnesium deficiency may cause chondrocalcinosis, and there is anecdotal evidence that magnesium supplementation may reduce or alleviate symptoms. [7] In some cases, arthritis from injury can cause chondrocalcinosis. [8] Other causes of chondrocalcinosis include: [4] Hypercalcaemia, especially when caused by hyperparathyroidism; Arthritis ...
Crystal arthropathy is a class of joint disorder (called arthropathy) that is characterized by accumulation of tiny crystals in one or more joints. Polarizing microscopy and application of other crystallographic techniques have improved identification of different microcrystals including monosodium urate , calcium pyrophosphate dihydrate ...
For example, gout in ankles or gout in knee joints may also occur. Gout in hands is less common but can happen. In this situation, it usually affects small joints in the fingers.
Thus, it is also recommended that patients with gout adhere to a diet rich in fiber, vegetables, and whole grains, while limiting the intake of alcohol and fatty foods. [ 82 ] There is also an uncommon form of gout that is known as pseudogout , which is caused by the formation of calcium pyrophosphate crystals in the joint. [ 86 ]
Gout (/ ɡ aʊ t / GOWT [7]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [2] [8] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [9]
Pseudogout (also referred to as calcium pyrophosphate dihydrate crystal deposition disease) is another type of crystalline arthritis that presents very similarly to gout but is caused by the deposition of rhomboid-shaped calcium pyrophosphate dihydrate (CPPD) crystals. The knees, wrists, and fingers are the most common joints affected by ...
Patients with a fever, suspected flare of existing arthritis, or unknown cause of joint effusion should undergo arthrocentesis with synovial fluid analysis. Samples of synovial fluid can be analyzed for gross appearance, presence of crystals, white blood cell count with differential, red blood cell count, and bacterial culture.