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  2. Niraparib/abiraterone acetate - Wikipedia

    en.wikipedia.org/wiki/Niraparib/abiraterone_acetate

    Niraparib/abiraterone acetate, sold under the brand name Akeega, is a fixed-dose combination anti-cancer medication used for the treatment of prostate cancer. [2] It contains niraparib , a poly (ADP-ribose) polymerase (PARP) inhibitor (antineoplastic agent), and abiraterone acetate , a CYP17 inhibitor (hormone antagonist).

  3. Abiraterone acetate - Wikipedia

    en.wikipedia.org/wiki/Abiraterone_acetate

    Abiraterone acetate is used in combination with prednisone, a corticosteroid, as a treatment for mCRPC (previously called hormone-resistant or hormone-refractory prostate cancer). [2] [6] [5] [4] This is a form of prostate cancer that is not responding to first-line androgen deprivation therapy or treatment with androgen receptor antagonists.

  4. Management of prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Management_of_prostate_cancer

    For men over 64 with prostate cancer limited to the pelvis, using fewer, larger doses of radiation (hypofractionation) results in similar overall survival rates. [28] The risk of dying from prostate cancer or having acute bladder side effects may be similar to that of longer radiation treatment. [28]

  5. Androgen deprivation therapy - Wikipedia

    en.wikipedia.org/wiki/Androgen_deprivation_therapy

    Androgen deprivation therapy (ADT), also called androgen ablation therapy or androgen suppression therapy, is an antihormone therapy whose main use is in treating prostate cancer. Prostate cancer cells usually require androgen hormones, such as testosterone, to grow. ADT reduces the levels of androgen hormones, with drugs or surgery, to prevent ...

  6. Δ4-Abiraterone - Wikipedia

    en.wikipedia.org/wiki/Δ4-Abiraterone

    Δ 4-Abiraterone (D4A; code name CB-7627), also known as 17-(3-pyridyl)androsta-4,16-dien-3-one, is a steroidogenesis inhibitor and active metabolite of abiraterone acetate, a drug which is used in the treatment of prostate cancer and is itself a prodrug of abiraterone (another active metabolite of abiraterone acetate). [1]

  7. Prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer

    Prostate cancer is a major topic of ongoing research. From 2016 to 2020, over $1.26 billion was invested in prostate cancer research, representing around 5% of global cancer research funds. [122] This places prostate cancer 10th among 18 common cancer types in funding per cancer death, and 9th in funding per disability-adjusted life year lost ...

  8. Selenium and Vitamin E Cancer Prevention Trial - Wikipedia

    en.wikipedia.org/wiki/Selenium_and_Vitamin_E...

    A 2011 study based on the trial found that the risk of prostate cancer was elevated by 17% in the group that took vitamin E supplements, which was statistically significant. [8] [13] A 2014 study based on SELECT data found that selenium supplementation increased the risk of high-grade prostate cancer in men who had a higher baseline selenium ...

  9. Prostate brachytherapy - Wikipedia

    en.wikipedia.org/wiki/Prostate_brachytherapy

    LDR prostate brachytherapy (seed or polymer source implantation) is a very effective treatment for low to high risk localized cancer, with patients rapidly returning to normal activities. [15] Although patients may experience urinary problems for the first six months or so after their implant, these usually settle down and lasting problems are ...

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