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2. Dipyridamole - Wikipedia

   en.wikipedia.org/wiki/Dipyridamole

   Dipyridamole (trademarked as Persantine and others) is an antiplatelet drug of the nucleoside transport inhibitor and PDE3 inhibitor class that inhibits blood clot formation when given chronically and causes blood vessel dilation when given at high doses over a short time.

3. AOH1996 - Wikipedia

   en.wikipedia.org/wiki/AOH1996

   AOH1996 was created to target a post-translationally modified isoform of PCNA, termed caPCNA, which is preferentially found in cancer cells. PCNA is crucial in the body for DNA repair, but targeting it is difficult because of its role in healthy cells.

4. List of therapeutic monoclonal antibodies - Wikipedia

   en.wikipedia.org/wiki/List_of_therapeutic...

   non-small cell lung cancer: Anatumomab mafenatox [17] Fab: mouse: Tumor-associated glycoprotein 72 (TAG-72) non-small cell lung cancer: Andecaliximab [18] mab: chimeric: gelatinase B: gastric cancer or gastroesophageal junction adenocarcinoma Anetumab ravtansine [4] mab: human: mesothelin (MSLN) cancer Anifrolumab [4] Saphnelo: mab: human: IFN ...

5. Targeted therapy - Wikipedia

   en.wikipedia.org/wiki/Targeted_therapy

   Pembrolizumab (Keytruda) binds to PD-1 proteins found on T cells. Pembrolizumab blocks PD-1 and help the immune system kill cancer cells. [23] It is used to treat melanoma, Hodgkin's lymphoma, non-small cell lung carcinoma and several other types of cancer. [24] Rituximab targets CD20 found on B cells. It is used in non Hodgkin lymphoma

6. 6-Diazo-5-oxo-L-norleucine - Wikipedia

   en.wikipedia.org/wiki/6-Diazo-5-oxo-L-norleucine

   DON was tested as chemotherapeutic agent in different clinical studies, but was never approved. In 2019, DON was shown to kill tumor cells while reversing disease symptoms and improve overall survival in late-stage experimental glioblastoma in mice, when combined with calorie-restricted ketogenic diet. [5]

7. Tumor-infiltrating lymphocytes - Wikipedia

   en.wikipedia.org/wiki/Tumor-infiltrating_lymphocytes

   The cells are activated and grown prior to transfusion into the recipient (tumor bearer). In Adoptive T cell transfer therapy, TILs are expanded ex vivo from surgically resected tumors that have been cut into small fragments or from single cell suspensions isolated from the tumor fragments. Multiple individual cultures are established, grown ...

8. Tumor microenvironment - Wikipedia

   en.wikipedia.org/wiki/Tumor_microenvironment

   T cells must replicate after arriving at the tumor site to effectively kill the cancer cells, survive hostile elements and migrate through the stroma to the cancer cells. This is affected by the tumor microenvironment. The draining lymph nodes are the likely location for cancer specific T cell replication, although this also occurs within the ...

9. List of breast cancer cell lines - Wikipedia

   en.wikipedia.org/wiki/List_of_breast_cancer_cell...

   Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are primarily used in breast cancer ...