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The use of warfarin itself as a rat poison is declining, because many rat populations have developed resistance to it, [109] and poisons of considerably greater potency have become available. However, as of 2023 [update] warfarin continued to be considered a valuable tool for rodent control which minimised risk to other species.
Typical rat poison bait station (Germany, 2010) Rodenticides are chemicals made and sold for the purpose of killing rodents.While commonly referred to as "rat poison", rodenticides are also used to kill mice, woodchucks, chipmunks, porcupines, nutria, beavers, [1] and voles.
The rodenticide chemicals are sometimes incorrectly referred to as "coumadins" rather than 4-hydroxycoumarins ("Coumadin" is a brand name for warfarin). They are also referred to as "coumarins," in reference to their derivation, although this term also may be deceptive since coumarin itself, as noted, is not active in clotting, and is used ...
Warning label on a tube of rat poison containing bromadiolone on a dike of the Scheldt river in Steendorp, Belgium. Bromadiolone is a potent anticoagulant rodenticide.It is a second-generation 4-hydroxycoumarin derivative and vitamin K antagonist, often called a "super-warfarin" for its added potency and tendency to accumulate in the liver of the poisoned organism.
In the mid-1970s, warfarin resistance began to appear in mice, which prompted a need for alternative rodenticides. [12] This led to the introduction of brodifacoum in 1975, followed by d-CON's introduction of it in the commercial market in the 1980s. [13] The compound works similarly to warfarin, but requires fewer doses.
The law will place a permanent moratorium on a rat poison that unintentionally also kills predators, such as mountain lions, coyotes and other animals.
Brodifacoum is a 4-hydroxycoumarin anticoagulant, with a similar mode of action to its historical predecessors dicoumarol and warfarin.However, due to very high potency and long duration of action (elimination half-life of 20 – 130 days), it is characterised as a "second-generation" or "superwarfarin" anticoagulant.
Alabama head coach Nick Saban continues to have fun with his “rat poison” saying that he had a few weeks after his team took down Georgia in the SEC Championship Game. Not many people around ...
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