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  2. Minor allele frequency - Wikipedia

    en.wikipedia.org/wiki/Minor_allele_frequency

    1. Introduce the reference of a SNP of interest, as an example: rs429358, in a database (dbSNP or other). 2. Find MAF/MinorAlleleCount link. MAF/MinorAlleleCount: C=0.1506/754 (1000 Genomes, where number of genomes sampled = N = 2504); [4] where C is the minor allele for that particular locus; 0.1506 is the frequency of the C allele (MAF), i.e. 15% within the 1000 Genomes database; and 754 is ...

  3. Allele frequency - Wikipedia

    en.wikipedia.org/wiki/Allele_frequency

    Allele frequency, or gene frequency, is the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage. [1] Specifically, it is the fraction of all chromosomes in the population that carry that allele over the total population or sample size.

  4. Allele frequency spectrum - Wikipedia

    en.wikipedia.org/wiki/Allele_frequency_spectrum

    The folded frequency spectrum stores the observed counts of the minor (most rare) allele frequencies. The folded spectrum can be calculated by binning together the i {\displaystyle i} th and ( n − i ) {\displaystyle (n-i)} th entries from the unfolded spectrum, where n {\displaystyle n} is the number of sampled individuals.

  5. Genotype frequency - Wikipedia

    en.wikipedia.org/wiki/Genotype_frequency

    if the allele A frequency is denoted by the symbol p and the allele a frequency denoted by q, then p+q=1. For example, if p=0.7, then q must be 0.3. In other words, if the allele frequency of A equals 70%, the remaining 30% of the alleles must be a, because together they equal 100%. [5]

  6. Quantitative genetics - Wikipedia

    en.wikipedia.org/wiki/Quantitative_genetics

    The "base" allele frequencies of the example are those of the potential gamodeme: the frequency of A is p g = 0.75, while the frequency of a is q g = 0.25. [ White label " 1 " in the diagram.] Five example actual gamodemes are binomially sampled out of this base ( s = the number of samples = 5), and each sample is designated with an "index" k ...

  7. Fixation index - Wikipedia

    en.wikipedia.org/wiki/Fixation_index

    If ¯ is the average frequency of an allele in the total population, is the variance in the frequency of the allele among different subpopulations, weighted by the sizes of the subpopulations, and is the variance of the allelic state in the total population, F ST is defined as [2]

  8. Child-abusing mommy bloggers Ruby Franke and friend ... - AOL

    www.aol.com/child-abusing-mommy-bloggers-ruby...

    A Utah man claims he lost more than $1 million after his spouse became enthralled with disgraced Utah parenting bloggers Ruby Franke and Jodi Hildebrandt's bizarre "counseling."

  9. Hardy–Weinberg principle - Wikipedia

    en.wikipedia.org/wiki/Hardy–Weinberg_principle

    Mutation will have a very subtle effect on allele frequencies through the introduction of new allele into a population. Mutation rates are of the order 10 −4 to 10 −8, and the change in allele frequency will be, at most, the same order. Recurrent mutation will maintain alleles in the population, even if there is strong selection against them.