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Reduced dopamine D1 receptors and dopamine D2 receptors in the striatum have been reported in people with OCD, along with both increased and decreased reports of dopamine transporter (DAT) binding. While antipsychotics are sometimes used to treat refractory OCD, they frequently fail in treating or exacerbate OCD symptoms.
The Connection Between Her OCD and Her Sobriety: “When I was actively drinking alcohol, I was masking symptoms by numbing out. My brain was so loud—and drinking quieted the noise. My brain was ...
[2] OCD is a mental disorder characterized by obsessions and/or compulsions. [3] An obsession is defined as "a recurring thought, image, or urge that the individual cannot control". [4] Compulsion can be described as a "ritualistic behavior that the person feels compelled to perform". [4]
[38] [87] Obsessive–compulsive disorder symptoms tend to develop more frequently in children 10–14 years of age, with males displaying symptoms at an earlier age, and at a more severe level than females. [88] In children, symptoms can be grouped into at least four types, including sporadic and tic-related OCD. [36]
Transgenerational stress in humans, as in animal models, induces effects influencing social behavior, reproductive success, cognitive ability, and stress response. [3] Similar to animal models, human studies have investigated the role of epigenetics and transgenerational inheritance molecularly as it relates to the HPA system.
[12] [59] Postpartum OCD occurs mainly in women who may already have OCD, perhaps in a mild or undiagnosed form. Postpartum depression and OCD may be comorbid (often occurring together). And though physicians may focus more on the depressive symptoms, one study found that obsessive thoughts did accompany postpartum depression in 57% of new mothers.
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