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The chicken embryo is a unique model that overcomes many limitations to studying the biology of cancer in vivo. The chorioallantoic membrane (CAM), a well-vascularized extra-embryonic tissue located underneath the eggshell, has a successful history as a biological platform for the molecular analysis of cancer including viral oncogenesis, [8] carcinogenesis, [9] tumor xenografting, [1] [10] [11 ...
Stentor coeruleus, used in molecular biology (its genome has been sequenced), [5] and is studied as a model of single-cell regeneration.; Dictyostelium discoideum, used in molecular biology and genetics (its genome has been sequenced), and is studied as an example of cell communication, differentiation, and programmed cell death.
A humanized mouse is a genetically modified mouse that has functioning human genes, cells, tissues and/or organs. [1] Humanized mice are commonly used as small animal models in biological and medical research for human therapeutics.
Model organisms each have some particular experimental advantages which have enabled them to become popular among researchers. In one sense they are "models" for the whole animal kingdom, and in another sense they are "models" for human development, which is difficult to study directly for both ethical and practical reasons.
Organoids are derived from three kinds of human or animal stem cells—embryonic pluripotent stem cells (ESCs), adult somatic stem cells (ASCs), and induced pluripotent stem cells (iPSCs). These organoids are grown in vitro and mimic the structure and function of different organs such as the brain, liver, lung, kidney, and intestine. Organoids ...
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Cell-based models are mathematical models that represent biological cells as discrete entities. Within the field of computational biology they are often simply called agent-based models [1] of which they are a specific application and they are used for simulating the biomechanics of multicellular structures such as tissues. to study the influence of these behaviors on how tissues are organised ...
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