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  2. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Metformin inhibits cyclic AMP production, blocking the action of glucagon, and thereby reducing fasting glucose levels. [117] Metformin also induces a profound shift in the faecal microbial community profile in diabetic mice, and this may contribute to its mode of action possibly through an effect on glucagon-like peptide-1 secretion. [108]

  3. Diabetes management - Wikipedia

    en.wikipedia.org/wiki/Diabetes_management

    One of the most common drugs used in T2D, metformin is the drug of choice to help patients lower their blood sugar levels. Metformin is an example of a class of medicine called biguanides. [34] The medication works by reducing the new creation of glucose from the liver and by reducing absorption of sugar from food. [34]

  4. Is There a "Best Time" to Take Metformin? - AOL

    www.aol.com/best-time-metformin-115700262.html

    Take liquid metformin at the same time each day and with food. Just like with the tablet version, make it a habit to take liquid metformin at the same time to avoid missing doses and with food ...

  5. Cmax (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Cmax_(pharmacology)

    C max is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administered and before the administration of a second dose. [1] It is a standard measurement in pharmacokinetics.

  6. Pharmacokinetics - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics

    At a practical level, a drug's bioavailability can be defined as the proportion of the drug that reaches the systemic circulation. From this perspective the intravenous administration of a drug provides the greatest possible bioavailability, and this method is considered to yield a bioavailability of 1 (or 100%).

  7. Hyperglycemia - Wikipedia

    en.wikipedia.org/wiki/Hyperglycemia

    In general, the normal range for most people (fasting adults) is about 4 to 6 mmol/L or 80 to 110 mg/dL. (where 4 mmol/L or 80 mg/dL is "optimal".) A subject with a consistent range above 7 mmol/L or 126 mg/dL is generally held to have hyperglycemia, whereas a consistent range below 4 mmol/L or 70 mg/dL is considered hypoglycemic.

  8. Dawn phenomenon - Wikipedia

    en.wikipedia.org/wiki/Dawn_phenomenon

    Notably throughout this process glucagon levels remain unchanged and the increased levels of cortisol observed overnight do not appear to be involved. [ 5 ] [ 6 ] Observed hyperglycemia secondary to the dawn phenomenon is often defined as an increase in blood glucose of at least >1.1 mmol/L (20 mg/dL) between the lowest level at night and the ...

  9. Top aging expert says these 4 FDA-approved drugs hold promise ...

    www.aol.com/finance/global-aging-doctor-says-4...

    GLP-1s suppress appetite and have been shown to improve blood sugar levels for those with type 2 diabetes. ... reads one paper published in the Mayo Clinic ... while metformin makes the list as a ...

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