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  2. Cyclobenzaprine (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/cyclobenzaprine-oral...

    Cyclobenzaprine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of this medicine's side effects. This medicine is available only with your doctor's prescription.

  3. Tizanidine (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/tizanidine-oral-route/...

    Tizanidine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects. This medicine is available only with your doctor's prescription.

  4. Metaxalone (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/metaxalone-oral-route/...

    Metaxalone is a skeletal muscle relaxant. It acts on the central nervous system (CNS) to relax muscles. This medicine is available only with your doctor's prescription.

  5. Orphenadrine (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/orphenadrine-oral...

    Orphenadrine acts in the central nervous system (CNS) to produce its muscle relaxant effects. Orphenadrine also has other actions (anticholinergic) that produce its helpful effects in Parkinson's disease.

  6. Treatment for Restless Legs Syndrome Focuses on Relieving the...

    newsnetwork.mayoclinic.org/discussion/treatment-for...

    Certain medications used to treat painful nerve conditions and epilepsy, such as gabapentin, also may effectively treat RLS. Other prescription drugs, including opioid analgesics, muscle relaxants and sleep medications, are sometimes used to help combat RLS symptoms as well.

  7. Methocarbamol (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/methocarbamol-oral...

    Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, muscle ...

  8. Ropinirole (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/ropinirole-oral-route/...

    Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics.

  9. Baclofen (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/baclofen-oral-route/...

    Baclofen acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects. Baclofen may also be used to relieve other conditions as determined by your doctor.

  10. Clonazepam (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/clonazepam-oral-route/...

    Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, barbiturates or seizure medicines, muscle relaxants, or anesthetics (numbing medicines), including some dental anesthetics.

  11. Risks for other drugs interacting with opioid medications

    newsnetwork.mayoclinic.org/discussion/risks-for-other...

    Muscle relaxers, such as cyclobenzaprine (Amrix) Other opioid medications; Sedatives, such as diazepam (Valium)