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Hexokinase IV is present in the liver, pancreas, hypothalamus, small intestine, and perhaps certain other neuroendocrine cells, and plays an important regulatory role in carbohydrate metabolism. In the β cells of the pancreatic islets , it serves as a glucose sensor to control insulin release, and similarly controls glucagon release in the α ...
Hexokinase I, also known as hexokinase A and HK1, is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. Hexokinases phosphorylate glucose to produce glucose-6-phosphate (G6P), the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of ...
Hexokinase II, also known as Hexokinase B and HK2, is an enzyme which in humans is encoded by the HK2 gene on chromosome 2. [5] [6] Hexokinases phosphorylate glucose to produce glucose 6-phosphate, the first step in most glucose metabolism pathways. Hexokinase II is the predominant hexokinase form found in skeletal muscle.
Hexokinase deficiency is an extremely rare autosomal recessive condition that falls under the category of erythroenzymopathies, or defects in red cell enzymes. [2] Hexokinase deficiency manifests is associated with chronic nonspherocytic hemolytic anemia. [3] Hemolytic anemia seems to be the only clinical sign of hexokinase deficiency. [4]
Mutations in the hexokinase gene can lead to a hexokinase deficiency which can cause nonspherocytic hemolytic anemia. [27] Phosphofructokinase, or PFK, catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is an important point in the regulation of glycolysis. High levels of ATP, H +, and citrate inhibit PFK. If ...
The first generation (generation I) of the Pokémon franchise features the original 151 fictional species of monsters introduced to the core video game series in the 1996 Game Boy games Pocket Monsters Red, Green and Blue (known as Pokémon Red, Green and Blue outside of Japan). (Later Pokemon Yellow and Blue were released Nationally)
“Red dye No. 40 can still cause behavioral disruptions, especially in children. Currently, it is not listed as a carcinogen, but it does contain benzene , which has been correlated with cancer.”
Pokémon Red Version and Pokémon Blue Version are 1996 role-playing video games (RPGs) developed by Game Freak and published by Nintendo for the Game Boy.They are the first installments of the Pokémon video game series, and were first released in Japan as Pocket Monsters Red [a] and Pocket Monsters Green, [b] followed by the special edition Pocket Monsters Blue [c] later that year.