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Osteomalacia is a disease characterized by the softening of the bones caused by impaired bone metabolism primarily due to inadequate levels of available phosphate, calcium, and vitamin D, or because of resorption of calcium. The impairment of bone metabolism causes inadequate bone mineralization.
A lack of exposure to sunlight, the natural process of aging, and high levels of body fat can all contribute to vitamin D deficiency, which can lead to osteoporosis, bone and joint pain, and ...
Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.
The U.S. Preventive Services Task Force say vitamin D supplements do not reduce the risk of falls or bone fractures in healthy older adults. The draft recommendation notes vitamin D can be helpful ...
Both vitamin D and D3 have their own health benefits. ... symptoms of a vitamin D deficiency may include: Muscle or bone pain. ... which can lead to a buildup of calcium in the bloodstream and ...
X-linked hypophosphatemia (XLH) is an X-linked dominant form of rickets (or osteomalacia) that differs from most cases of dietary deficiency rickets in that vitamin D supplementation does not cure it. It can cause bone deformity including short stature and genu varum (bow-leggedness).
Vitamin D 3 (cholecalciferol) is the preferred form since it is more readily absorbed than vitamin D 2. Most dermatologists recommend vitamin D supplementation as an alternative to unprotected ultraviolet exposure due to the increased risk of skin cancer associated with sun exposure. Endogenous production with full body exposure to sunlight is ...
An excess of vitamin D causes abnormally high blood concentrations of calcium, which can cause overcalcification of the bones, soft tissues, heart and kidneys. In addition, hypertension can result. [2] Symptoms of vitamin D toxicity may include the following: Dehydration; Vomiting; Diarrhea; Decreased appetite; Irritability; Constipation ...