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Pseudomonas aeruginosa is a common encapsulated, Gram-negative, aerobic–facultatively anaerobic, rod-shaped bacterium that can cause disease in plants and animals, including humans.
Pseudomonas infection refers to a disease caused by one of the species of the genus Pseudomonas. P. aeruginosa is a germ found in the environment and it is an opportunistic human pathogen most commonly infecting immunocompromised patients, such as those with cancer, diabetes, cystic fibrosis, [1] severe burns, AIDS, [2] or people who are very ...
The symptoms of these infections are caused by proteins secreted by the bacteria and may include pneumonia, blood poisoning, and urinary tract infections. [46] Pseudomonas aeruginosa is highly contagious and has displayed resistance to antibiotic treatments, making it difficult to manage effectively.
Pseudomonas aeruginosa can cause chronic opportunistic infections that have become increasingly apparent in immunocompromised patients and the ageing population of industrialised societies. The genome sequences of several pseudomonads have become available in recent years and researchers are beginning to use the data to make new discoveries ...
Pseudomonas aeruginosa. The molecule 2-heptyl-3-hydroxy-4-quinolone, also named the Pseudomonas quinolone signal (PQS), has been discovered as an intracellular link between the two major quorum sensing systems of P. aeruginosa; the las and rhl systems. [1]
The Pseudomonas exotoxin (or exotoxin A) is an exotoxin produced by Pseudomonas aeruginosa. [1] Vibrio cholerae produces a similar protein called the Cholix toxin 2] It inhibits elongation factor-2. It does so by ADP-ribosylation of EF2 using NAD+. This then causes the elongation of polypeptides to cease.
Studies also suggest the emergence of antibiotic resistance in P. aeruginosa. [5] In 2000, the complete genome of a Pseudomonas species was sequenced; more recently, the genomes of other species have been sequenced, including P. aeruginosa PAO1 (2000), P. putida KT2440 (2002), P. fluorescens Pf-5 (2005), P. fluorescens PfO-1, and P. entomophila ...
The strain of P. aeruginosa may spread from person-to-person, as was first seen in a long-term care center in Connecticut. [8] According to the CDC, VIM-GES-CRPA had not appeared in the United States until the outbreak. [9] In comparison, P. aeruginosa is "pretty much everywhere" in India, according to Christian Medical College researcher ...
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