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The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary ...
α-Melanocyte-stimulating hormone (α-MSH) is an endogenous peptide hormone and neuropeptide of the melanocortin family, with a tridecapeptide structure and the amino acid sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH 2.
The melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a G protein–coupled receptor that binds to a class of pituitary peptide hormones known as the melanocortins, which include adrenocorticotropic hormone (ACTH) and the different forms of melanocyte-stimulating hormone (MSH).
They are Adrenocorticotropic hormone (ACTH), a-melanocyte stimulating hormone (MSH), b-MSH, and g-MSH. In addition to agonists which activate melanocortin receptors , there are two antagonists which inhibit receptor activity, Agouti and Agouti-related protein (Agrp). Lastly, the ligand β-defensin 3 acts as a neutral melanocortin receptor ...
stimulates melanocytes to produce melanin: 44 Luteinizing hormone: LH Peptide: anterior pituitary: gonadotropes: LHR → cAMP: In female: ovulation. In male: stimulates Leydig cell production of testosterone. 45 Melanocyte stimulating hormone: MSH or α-MSH Peptide: anterior pituitary/pars intermedia: Melanotroph: melanocortin receptor → cAMP
A melanotroph (or melanotrope) is a cell in the pituitary gland that generates melanocyte-stimulating hormone (α‐MSH) from its precursor pro-opiomelanocortin. Chronic stress can induce the secretion of α‐MSH in melanotrophs and lead to their subsequent degeneration. [1]
The bottom line: Hormones and stress intertwine, influencing your scalp’s oil levels. Poor Hygiene: For some, washing hair too frequently can dry the scalp and strip the hair of its natural oils ...
17202 Ensembl ENSG00000166603 ENSMUSG00000047259 UniProt P32245 P56450 RefSeq (mRNA) NM_005912 NM_016977 RefSeq (protein) NP_005903 NP_058673 Location (UCSC) Chr 18: 60.37 – 60.37 Mb Chr 18: 66.99 – 66.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Melanocortin 4 receptor (MC 4 R) is a melanocortin receptor that in humans is encoded by the MC4R gene. It encodes the MC 4 R ...