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Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [10] The effectiveness of sertraline for depression is similar to that of other antidepressants such as Fluoxetine or Paroxetine. Sertraline is better tolerated than the older tricyclic antidepressants.
The use of SSRIs for the treatment of PPD is not a contraindication for breastfeeding. While antidepressants are excreted in breastmilk, the concentrations recorded in breastmilk are very low. [131] [132] Extensive research has shown that the use of SSRI's by women who are lactating is safe for the breastfeeding infant/child.
[187] [188] Fluvoxamine is an agonist of the σ 1 receptor, while sertraline is an antagonist of the σ 1 receptor, and paroxetine does not significantly interact with the σ 1 receptor. [187] [188] None of the SSRIs have significant affinity for the σ 2 receptor. [187] [188] Fluvoxamine has by far the strongest activity of the SSRIs at the σ ...
Some people may need antidepressants for a relatively short period (like while grieving the loss of a loved one), or they might need medication long-term, if the depression is chronic.
This means that while using sertraline, your body might have difficulty forming a normal blood clot if you cut or puncture your skin. You may experience nosebleeds or unexplained bruising.
SSRIs are modern antidepressants often used as a first-line treatment for major depressive disorder. Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram ...
Breastfeeding is associated with improved social and emotional health and development of the child. [1] The breastfeeding activity induces calming and analgesic effects in the infant. During this activity, their heart and metabolic rates decrease and their sensitivity to pain is reduced. [16]
For many antidepressants, this risk is highest during the first few weeks and months of treatment. ... or are breastfeeding. Once prescribed, escitalopram may take some time to start working. Don ...