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  2. Linezolid - Wikipedia

    en.wikipedia.org/wiki/Linezolid

    Linezolid is an antibiotic used for the treatment of infections caused by Gram-positive bacteria that are resistant to other antibiotics. [9] [10] Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA).

  3. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban bears a striking structural similarity to the antibiotic linezolid: both drugs share the same oxazolidinone-derived core structure. [39] Accordingly, rivaroxaban was studied for any possible antimicrobial effects and for the possibility of mitochondrial toxicity , which is a known complication of long-term linezolid use. [ 40 ]

  4. Drug of last resort - Wikipedia

    en.wikipedia.org/wiki/Drug_of_last_resort

    The use of a drug of last resort may be based on agreement among members of a patient's care network, including physicians and healthcare professionals across multiple specialties, or on a patient's desire to pursue a particular course of treatment and a practitioner's willingness to administer that course.

  5. Vancomycin-resistant Staphylococcus aureus - Wikipedia

    en.wikipedia.org/wiki/Vancomycin-resistant...

    When the minimum inhibitory concentration of vancomycin is > 2 µg/mL, alternative antibiotics should be used. The approach is to treat with at least one agent to which the bacteria known to be susceptible by in vitro testing. The agents that are used include daptomycin, linezolid, telavancin, ceftaroline, and quinupristin–dalfopristin.

  6. Sutezolid - Wikipedia

    en.wikipedia.org/wiki/Sutezolid

    Sutezolid is an investigational new drug that is being evaluated for the treatment of extensively drug-resistant tuberculosis. [1] It differs from linezolid by replacement of the morpholine oxygen with a sulfur atom. Like linezolid, sutezolid is a bacterial protein synthesis inhibitor.

  7. Phumeza Tisile - Wikipedia

    en.wikipedia.org/wiki/Phumeza_Tisile

    Tisile's successful treatment relied on linezolid, which was expensive in South Africa, at €35,000 (£27,760, US $47,323) per patient a two-year course, not including the other drugs in the cocktail. [4] [6] Owned by Pfizer, generic linezolid was not available in South Africa.

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  9. Pretomanid - Wikipedia

    en.wikipedia.org/wiki/Pretomanid

    Pretomanid is an antibiotic medication used for the treatment of multi-drug-resistant tuberculosis affecting the lungs. [4] [5] It is generally used together with bedaquiline and linezolid. [4] It is taken by mouth. [4] The most common side effects include nerve damage, acne, vomiting, headache, low blood sugar, diarrhea, and liver inflammation ...

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