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Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons. [7] HOXC6 plays a role in lymphoma. The HOXC6 isoform, HOXC6-2 is an active carcinogenic for gastric cancer.
HoxC6 was found to play an important role in gastrulation in the vertebrate Xenopus. However, gastrulation was also a target in the Drosophila Antp gene. The anterior–posterior pattern mechanism is highly conserved in these genes, as its function in Xenopus is clear, but it is unclear why it would be a target in Drosophila .
Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in the correct places of the body.
Move over, Wordle and Connections—there's a new NYT word game in town! The New York Times' recent game, "Strands," is becoming more and more popular as another daily activity fans can find on ...
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Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein.
BA.2.86 features more than 30 mutations compared to omicron XBB.1.5, which was the dominant variant for most of 2023 — it's also the strain targeted in the updated COVID-19 vaccine.
On e-commerce platforms like Etsy, TikTok Shop, eBay and Redbubble, sellers are hawking merchandise featuring designs inspired by the fatal shooting of UnitedHealthcare CEO Brian Thompson.