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Conversely, CPA at higher doses, for instance 100 mg/day or greater, has been reported to produce a variety of side effects in men including decreased libido, erectile dysfunction, gynecomastia, tiredness, weakness, decreased efficiency, weight gain, skin dryness, skin peeling, and decreased body hair (e.g., trunk and pubic region). [275
Some men present with symptoms, but they have normal testosterone levels, while others with low testosterone levels have no symptoms. The reasons for this phenomenon are currently unknown. [3] [6] In their late 40s and early 50s, some men may experience depression, loss of libido, erectile dysfunction, and other physical and emotional symptoms.
Bicalutamide may cause sexual dysfunction, including decreased sex drive and erectile dysfunction. [8] However, the rates of these side effects with bicalutamide monotherapy are very low. [ 8 ] In the EPC trial, at 7.4 years follow-up, the rates of decreased libido and impotence were only 3.6% and 9.3% in the 150 mg/day bicalutamide monotherapy ...
Sudden weight gain can be an early symptom of heart failure, according to the American Heart Association. Weight gain of more than two or three pounds within a 24 hour period may be a sign your ...
In both men and women, possible side effects of CPA include low sex hormone levels, reversible infertility, sexual dysfunction, fatigue, depression, weight gain, and elevated liver enzymes. With prolonged use, brain tumors prompting surgery are common, from 5% at high doses [ 16 ] to 2% at low doses.
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Some patients (especially younger ones) gain weight due to excessive appetite stimulation that exceeds the weight loss effect. [11] Increased appetite. [4] Increased sweating [11] Heat intolerance [11] Abnormal breast enlargement in men [12] Augmented calcium levels in the blood (by as much as 25% – known as hypercalcaemia). This can cause ...
In men, it causes impaired muscle and body hair development, gynecomastia, decreased height, erectile dysfunction, and sexual difficulties. If hypogonadism is caused by a disorder of the central nervous system (e.g., a brain tumor ), then this is known as central hypogonadism .
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