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Terbutaline as a treatment for premature labor is an off-label use not approved by the US FDA, who have warned that oral terbutaline is not effective and can cause severe heart problems or death, and while injectable terbutaline can be used for premature labor in emergency situations in a hospital setting, it should only be used for short ...
Mechanism of action Description Possible contraindications Maternal side effects Fetal and neonatal side effects Terbutaline (Brethine) β 2 agonist: Off-label use, FDA has advised that injectable terbutaline should only be used in urgent situations, and that the oral form of the drug should never be used [9]
Salbutamol and terbutaline are also both available in oral forms. [11] In addition, several of these medications are available in intravenous forms, including both salbutamol and terbutaline . It can be used in this form in severe cases of asthma , but it is more commonly used to suppress premature labor because it also relaxes uterine muscle ...
Bambuterol acts as a cholinesterase inhibitor, and can prolong the duration of action of suxamethonium (succinylcholine) and other drugs whose breakdown in the body depends on cholinesterase function. [1] Butyrylcholinesterase activity returns to normal approximately two weeks after bambuterol is stopped. [3]
The mechanism of action of aspirin involves irreversible inhibition of the enzyme cyclooxygenase; [17] therefore suppressing the production of prostaglandins and thromboxanes, thus reducing pain and inflammation. This mechanism of action is specific to aspirin and is not constant for all nonsteroidal anti-inflammatory drugs (NSAIDs). Rather ...
The action of sympathomimetic drugs can be classified as direct and indirect action. The direct mode of activating adrenergic receptors involve the mimicking of endogenous molecules through agonist molecules, and the indirect mode of action involve mechanisms of increasing the release, or decreasing the breakdown and removal of noradrenaline. [11]
A mechanism of action of a chemical could be "binding to DNA" while its broader mode of action would be "transcriptional regulation". [3] However, there is no clear consensus and the term mode of action is also often used, especially in the study of pesticides, to describe molecular mechanisms such as action on specific nuclear receptors or ...
Ritodrine is a short-acting β 2-adrenoreceptor agonist — a class of medication used for smooth muscle relaxation (other similar drugs are used in asthma or other pulmonary diseases such as salbutamol (albuterol)).