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Cell therapy to improve nerve regeneration is also being researched. In one study mononuclear cells, cells with one nucleus, were used to repair the sciatic nerve, a large nerve running through the leg to the butt, followed by epineurial repair. Wistar rats were divided into groups of a control, epineurial sutures, medium after suture and ...
The neurosurgical team at Seattle Children's Hospital has modified the surgical approach described above by tailoring the selection of nerve root sectioning to the individual patient. This technique selectively analyzes each individual nerve root with electromyography to separate dorsal and ventral nerve roots through comparison of stimulus ...
A nerve guidance conduit (also referred to as an artificial nerve conduit or artificial nerve graft, as opposed to an autograft) is an artificial means of guiding axonal regrowth to facilitate nerve regeneration and is one of several clinical treatments for nerve injuries. When direct suturing of the two stumps of a severed nerve cannot be ...
These nerve cells, or neurons, called Vsx2, are present in the brain stem and the spinal cord and have been found to play a key role in the recovery of motor function after spinal cord injury.
A nerve decompression is a neurosurgical procedure to relieve chronic, direct pressure on a nerve to treat nerve entrapment, a pain syndrome characterized by severe chronic pain and muscle weakness. In this way a nerve decompression targets the underlying pathophysiology of the syndrome and is considered a first-line surgical treatment option ...
[8] [11] Microdiscectomy is another surgical alternative which uses small incisions, and a miniature camera for viewing, to enter the spinal cord and release pressure on the nerve roots. [5] [8] Laminoplasty and spinal fusion surgeries are other alternative surgical procedures that can be performed. However, they are relatively new methods ...
A vestibular neurectomy is an operation that severs the vestibular nerve, which contributes to balance, while sparing the cochlear nerve, which contributes to hearing. The procedure has the potential to relieve vertigo, but may preserve the ability to hear. [7] It is important to note that this procedure will not reverse the effects of deafness.
When a nerve axon is severed, the end still attached to the cell body is labeled the proximal segment, while the other end is called the distal segment. After injury, the proximal end swells and experiences some retrograde degeneration, but once the debris is cleared, it begins to sprout axons and the presence of growth cones can be detected.