Search results
Results from the WOW.Com Content Network
Growth factors (5 C, 51 P) GTP-binding protein regulators (1 C, 12 P) H. Heat shock proteins (48 P) L. Lectins (5 C, 24 P) M. ... Pages in category "Proteins by function"
Numerous protein structures are the result of rational design and do not exist in nature. Proteins can be designed from scratch (de novo design) or by making calculated variations on a known protein structure and its sequence (known as protein redesign). Rational protein design approaches make protein-sequence predictions that will fold to ...
A protein superfamily is the largest grouping of proteins for which common ancestry can be inferred (see homology). Usually this common ancestry is inferred from structural alignment [ 1 ] and mechanistic similarity, even if no sequence similarity is evident. [ 2 ]
General: General and multiple functions; interactions with proteins, lipids, small molecules, and ions. Other/Unknown: an unknown function, viral proteins , or toxins . Each domain superfamily in SCOP classes a to g were manually annotated using this scheme [ 17 ] [ 18 ] [ 19 ] and the information used was provided by SCOP , [ 10 ] InterPro ...
Proteins having the same shape and some similarity of sequence and/or function are placed in "families", and are assumed to have a closer common ancestor. Similar to CATH and Pfam databases, SCOP provides a classification of individual structural domains of proteins, rather than a classification of the entire proteins which may include a ...
A protein family is a group of evolutionarily related proteins. In many cases, a protein family has a corresponding gene family, in which each gene encodes a corresponding protein with a 1:1 relationship. The term "protein family" should not be confused with family as it is used in taxonomy.
The CATH Protein Structure Classification database is a free, publicly available online resource that provides information on the evolutionary relationships of protein domains. It was created in the mid-1990s by Professor Christine Orengo and colleagues including Janet Thornton and David Jones , [ 2 ] and continues to be developed by the Orengo ...
When given a protein pair to classify, RFD first creates a representation of the protein pair in a vector. [9] The vector contains all the domain types used to train RFD, and for each domain type the vector also contains a value of 0, 1, or 2. If the protein pair does not contain a certain domain, then the value for that domain is 0.