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The low protein theory for the pathogenesis of kwashiorkor has been used to teach that capillary exchange between the lymphatic system and circulating blood is impaired by a reduced oncotic (i.e. colloid osmotic pressure, COP) in the blood, as a consequence of inadequate protein intake, so that the hydrostatic pressure gradient, which favors ...
The envelope (E) protein is the smallest and least well-characterized of the four major structural proteins found in coronavirus virions. [ 2 ] [ 3 ] [ 4 ] It is an integral membrane protein less than 110 amino acid residues long; [ 2 ] in SARS-CoV-2 , the causative agent of Covid-19 , the E protein is 75 residues long. [ 5 ]
The protease is important in the processing of the coronavirus replicase polyprotein . It is the main protease in coronaviruses and corresponds to nonstructural protein 5 (nsp5). [6] It cleaves the coronavirus polyprotein at 11 conserved sites. The 3CL protease has a cysteine-histidine catalytic dyad at its active site. [4]
Coronaviruses exhibit coronavirus spike protein, also known as the S protein, on their surfaces; S is a class I fusion protein and is responsible for mediating viral entry as the first step in viral infection. [10] It is highly antigenic and accounts for most antibodies produced by the immune system in response to infection.
The M protein is a transmembrane protein with three transmembrane domains and is around 230 amino acid residues long. [8] [9] In SARS-CoV-2, the causative agent of COVID-19, the M protein is 222 residues long. [10] Its membrane topology orients the C-terminus toward the cytosolic face of the membrane and thus into the interior of the virion.
Protein–energy undernutrition (PEU), once called protein–energy malnutrition (PEM), is a form of malnutrition that is defined as a range of conditions arising from coincident lack of dietary protein and/or energy in varying proportions. The condition has mild, moderate, and severe degrees.
Val Kilmer is stepping back into the spotlight. The "Top Gun" actor made a very rare public appearance on Monday at a charity basketball game, where he wore a button-down shirt painted with the ...
Spike (S) glycoprotein (sometimes also called spike protein, [2] formerly known as E2 [3]) is the largest of the four major structural proteins found in coronaviruses. [4] The spike protein assembles into trimers that form large structures, called spikes or peplomers, [3] that project from the surface of the virion.