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Cell nuclei stained blue. Papanicolaou stain (also Papanicolaou's stain and Pap stain) is a multichromatic (multicolored) cytological staining technique developed by George Papanicolaou in 1942. [1][2][3] The Papanicolaou stain is one of the most widely used stains in cytology, [1] where it is used to aid pathologists in making a diagnosis.
Pap tests can usually be performed during pregnancy up to at least 24 weeks of gestational age. [34] Pap tests during pregnancy have not been associated with increased risk of miscarriage. [34] An inflammatory component is commonly seen on Pap smears from pregnant women [35] and does not appear to be a risk for subsequent preterm birth. [36]
It is a component of Papanicolaou stains together with eosin Y and bismarck brown Y. [1] In pap smears, Light Green SF confers a blue staining for the cytoplasm of active cells such as columnar cells, parabasal squamous cells, and intermediate squamous cells. [3] It usually comes as a disodium salt. Its maximum absorption is at 630 (422) nm.
Pap stain. Gynecologic cytology, also gynecologic cytology, is a field of pathology concerned with the investigation of disorders of the female genital tract. The most common investigation in this field is the Pap test, which is used to screen for potentially precancerous lesions of the cervix. Cytology can also be used to investigate disorders ...
Cytopathology (from Greek κύτος, kytos, "a hollow"; [1] πάθος, pathos, "fate, harm"; and -λογία, -logia) is a branch of pathology that studies and diagnoses diseases on the cellular level. The discipline was founded by George Nicolas Papanicolaou in 1928. Cytopathology is generally used on samples of free cells or tissue ...
Koilocyte. ThinPrep pap smear with group of normal cervical cells on left and HPV -infected cells showing features typical of koilocytes: enlarged (x2 or x3) nuclei and hyperchromasia. A koilocyte is a squamous epithelial cell that has undergone a number of structural changes, which occur as a result of infection of the cell by human ...
Clue cell. Micrograph of a clue cell (center), covered in bacteria, as compared to an unremarkable squamous cell at bottom left, and a neutrophil at bottom center. Pap stain. Clue cells are epithelial cells of the vagina that get their distinctive stippled appearance by being covered with bacteria. The etymology behind the term "clue" cell ...
I have a family history of melanoma, and I’m very fair-skinned—my childhood nickname was Casper. So, 13 years ago, when an unusual spot appeared on my wrist, I was quick to point it out to my ...