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  2. Omeprazole - Wikipedia

    en.wikipedia.org/wiki/Omeprazole

    Omeprazole was a subject of a patent litigation in the U.S. [66] The invention involved application of two different coatings to a drug in pill form to ensure that the omeprazole did not disintegrate before reaching its intended site of action in stomach. Although the solution by means of two coating was obvious, the patent was found valid ...

  3. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    This list is not limited to drugs that were ever approved by the FDA. Some of them (lumiracoxib, rimonabant, tolrestat, ximelagatran and ximelidine, for example) were approved to be marketed in Europe but had not yet been approved for marketing in the US, when side effects became clear and their developers pulled them from the market.

  4. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [11] [12] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [6]

  5. Experts Warn Against Viral "Sleepmaxxing" Trend - AOL

    www.aol.com/experts-warn-against-viral-sleepmax...

    In fact, adults need 7 to 8 hours of high-quality sleep every night for our bodies to function at their best. If you don’t get enough sleep one night, the negative effects can linger until you ...

  6. Jay Leno Explains Why He Only Sleeps 4 Hours a Night: 'I'm ...

    www.aol.com/jay-leno-explains-why-only-183204136...

    Jay Leno is sharing why he just does not sleep much. The comedian, 74, made headlines back in December 2024 when he revealed he only sleeps about four hours each night during an appearance on Bill ...

  7. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Most of these medications are benzimidazole derivatives, related to omeprazole, but imidazopyridine derivatives such as tenatoprazole have also been developed. [77] Potassium-competitive inhibitors such as revaprazan reversibly block the potassium-binding site of the proton pump, acting more quickly, but are not available in most countries.

  8. Gisèle Pélicot's Ex-Husband, Who Was Convicted of Drugging ...

    www.aol.com/gis-le-p-licots-ex-150144947.html

    Dominique Pélicot — who was found guilty of drugging and raping his wife Gisèle Pélicot and inviting dozens to sexually assault her over the course of nearly 10 years — is facing renewed ...

  9. Acid peptic diseases - Wikipedia

    en.wikipedia.org/wiki/Acid_Peptic_Diseases

    Mucosal disruption in acid peptic disease patients can be caused by infection, barrier disruption, or gastric acid hypersecretion.Acid peptic diseases can arise due to various risk factors such as Helicobacter pylori infection, alcoholism, tobacco use, cocaine and amphetamine use, nonsteroidal anti-inflammatory drug use (NSAIDs), fasting, Zollinger-Ellison syndrome, angiogenesis inhibitor ...

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