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ALS is a motor neuron disease, which is a group of neurological disordersthat selectively affect motor neurons, the cells that control voluntary musclesof the body.[3] Other motor neuron diseases include primary lateral sclerosis(PLS), progressive muscular atrophy(PMA), progressive bulbar palsy, pseudobulbar palsy, and monomelic amyotrophy(MMA).
Multifocal motor neuropathy (MMN) is a progressively worsening condition where muscles in the extremities gradually weaken. The disorder, a pure motor neuropathy syndrome, is sometimes mistaken for amyotrophic lateral sclerosis (ALS) because of the similarity in the clinical picture, especially if muscle fasciculations are present.
A fasciculation, or muscle twitch, is a spontaneous, involuntary muscle contraction and relaxation, involving fine muscle fibers. [1] They are common, with as many as 70% of people experiencing them. [1] They can be benign, or associated with more serious conditions. [1] When no cause or pathology is identified, they are diagnosed as benign ...
Sharon Hesterlee, Ph.D. (Chief Research Officer)[3] Revenue. $63.7 million (in 2020)[4] Website. www.mda.org. Muscular Dystrophy Association(MDA) is an American nonprofit organizationdedicated to supporting people living with muscular dystrophy, ALS, and related neuromuscular diseases.
Prognosis. Good-Excellent. Benign fasciculation syndrome (BFS) is characterized by fasciculation (twitching) of voluntary muscles in the body. [1] The twitching can occur in any voluntary muscle group but is most common in the eyelids, arms, hands, fingers, legs, and feet. The tongue can also be affected.
Clonus is a sign of certain neurological conditions, particularly associated with upper motor neuron lesions involving descending motor pathways, and in many cases is accompanied by spasticity (another form of hyperexcitability). [1] Unlike small spontaneous twitches known as fasciculations (usually caused by lower motor neuron pathology ...
Specialty. Neurology, neuromuscular medicine. Neuromyotonia (NMT) is a form of peripheral nerve hyperexcitability that causes spontaneous muscular activity resulting from repetitive motor unit action potentials of peripheral origin. NMT along with Morvan's syndrome are the most severe types in the Peripheral Nerve Hyperexciteability spectrum.
Website. lesturnerals.org. The Les Turner ALS Foundation is a non-profit organization based in Chicago that provides amyotrophic lateral sclerosis (ALS) patient services; supports events, education and awareness about ALS; and funds ALS research. [2] Since it was founded, it has raised over $64 million.