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Melanoma is the most dangerous type of skin cancer; it develops from the melanin -producing cells known as melanocytes. [1] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye ( uveal melanoma ). [1] [2] In women, melanomas most commonly occur on the legs; while in men, on the back. [2]
Five anatomical levels are recognized, and higher levels have worsening prognostic implications. These levels are: [1] Level 1: Melanoma confined to the epidermis (melanoma in situ) Level 2: Invasion into the papillary dermis. Level 3: Invasion to the junction of the papillary and reticular dermis. Level 4: Invasion into the reticular dermis.
Superficial spreading melanoma ( SSM) is a type of skin cancer that typically starts as an irregularly edged dark spot typically on sun-exposed part of the body. [2] [3] The colour may be variable with dark, light and reddish shades; occasionally no color at all. [2] It typically grows in diameter before spreading to deeper tissue, forming a ...
The five-year survival rate for melanoma is more than 99% for people in the U.S. when it's discovered early, before it spreads to the lymph nodes and other organs, according to the Melanoma ...
Across 205,125 cases of male patients diagnosed with cutaneous invasive melanoma from 2004 to 2018 tracked by the National Cancer Database, the five-year survival rate was the lowest for Black men ...
Survival figures from British Association of Dermatologist Guidelines, 2002 Clark's level. Clark's level is a related staging system, used in conjunction with Breslow's depth, which describes the level of anatomical invasion of the melanoma in the skin. Clark's level was the primary factor in earlier AJCC staging schemas for melanoma.
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