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The reduced reserve capacity of organ systems, muscle, and bone create a state where the body is not capable of coping with stressors such as illness or falls. Frailty can lead to increased risk of adverse side effects, complications, and mortality. [12] Older age by itself is not what defines frailty, it is however a syndrome found in older ...
There are many proposed causes of sarcopenia and it is likely the result of multiple interacting factors. Understanding of the causes of sarcopenia is incomplete, however, changes in hormones, immobility, age-related muscle changes, nutrition, and neurodegenerative changes have all been recognized as potential causative factors.
Its causes are many and can be divided into conditions that have either true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscular junction disorders, such as myasthenia gravis. Muscle weakness can also ...
Common early symptoms include frequent tripping and falling and difficulty going up stairs. Foot drop in one or both feet can occur. [14] Part of the cause for this dysfunction is the early involvement of the quadriceps muscles. [1] Weakness of the tibialis anterior muscle is responsible for foot drop. Another common early symptom is trouble ...
Further causes of neuromuscular diseases are: Polymyositis. Inflammatory muscle disorders. Polymyalgia rheumatica (or "muscle rheumatism") is an inflammatory condition that mainly occurs in the elderly; it is associated with giant-cell arteritis (It often responds to prednisolone). [18] Polymyositis is an autoimmune condition in which the ...
Myasthenia or myasthaenia (my- from Greek: μυο meaning "muscle" + -asthenia [ἀσθένεια] meaning "weakness"), or simply muscle weakness, is a lack of muscle strength. The causes are many and can be divided into conditions that have either true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of ...
Muscle atrophy is the loss of skeletal muscle mass. It can be caused by immobility, aging, malnutrition, medications, or a wide range of injuries or diseases that impact the musculoskeletal or nervous system. Muscle atrophy leads to muscle weakness and causes disability.
Generalised weakness Symptoms include general muscle weakness and possible joint deformities. Disease progresses slowly, and lifespan is shortened. Congenital muscular dystrophy includes several disorders with a range of symptoms. Muscle degeneration may be mild or severe.
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